1MDX
Crystal structure of ArnB transferase with pyridoxal 5' phosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000271 | biological_process | polysaccharide biosynthetic process |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| A | 0009245 | biological_process | lipid A biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0046493 | biological_process | lipid A metabolic process |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0099620 | molecular_function | UDP-4-amino-4-deoxy-L-arabinose aminotransferase |
Functional Information from PDB Data
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE AKG A 401 |
| Chain | Residue |
| A | THR36 |
| A | HOH820 |
| A | TRP89 |
| A | HIS185 |
| A | GLU194 |
| A | PHE214 |
| A | ARG229 |
| A | LYS241 |
| A | ASN243 |
| A | HOH404 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 402 |
| Chain | Residue |
| A | SER61 |
| A | SER61 |
| A | GLU194 |
| A | GLU194 |
| A | LEU244 |
| A | LEU244 |
| A | PRO245 |
| A | ASN248 |
| A | ASN248 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 403 |
| Chain | Residue |
| A | PHE13 |
| A | ARG229 |
| A | GLY327 |
| A | LEU328 |
| A | HOH733 |
| A | HOH820 |
| A | HOH839 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"12429098","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"24460375","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"PubMed","id":"12429098","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1MDX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MDZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1b9h |
| Chain | Residue | Details |
| A | ASP160 | |
| A | TRP89 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1b9h |
| Chain | Residue | Details |
| A | ILE35 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1b9h |
| Chain | Residue | Details |
| A | ASP160 | |
| A | LYS188 | |
| A | TRP89 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1b9h |
| Chain | Residue | Details |
| A | ALA186 | |
| A | ASP160 | |
| A | TRP89 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1b9h |
| Chain | Residue | Details |
| A | HIS163 | |
| A | LYS188 |
