1M0I

Crystal Structure of Bacteriophage T7 Endonuclease I with a Wild-Type Active Site

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0008821	molecular_function	crossover junction DNA endonuclease activity
A	0008833	molecular_function	deoxyribonuclease IV (phage-T4-induced) activity
A	0015074	biological_process	DNA integration
A	0016032	biological_process	viral process
A	0016787	molecular_function	hydrolase activity
A	0039657	biological_process	symbiont-mediated suppression of host gene expression
A	0099015	biological_process	degradation of host chromosome by virus
A	1990238	molecular_function	double-stranded DNA endonuclease activity
B	0003677	molecular_function	DNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0008821	molecular_function	crossover junction DNA endonuclease activity
B	0008833	molecular_function	deoxyribonuclease IV (phage-T4-induced) activity
B	0015074	biological_process	DNA integration
B	0016032	biological_process	viral process
B	0016787	molecular_function	hydrolase activity
B	0039657	biological_process	symbiont-mediated suppression of host gene expression
B	0099015	biological_process	degradation of host chromosome by virus
B	1990238	molecular_function	double-stranded DNA endonuclease activity
C	0003677	molecular_function	DNA binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0008821	molecular_function	crossover junction DNA endonuclease activity
C	0008833	molecular_function	deoxyribonuclease IV (phage-T4-induced) activity
C	0015074	biological_process	DNA integration
C	0016032	biological_process	viral process
C	0016787	molecular_function	hydrolase activity
C	0039657	biological_process	symbiont-mediated suppression of host gene expression
C	0099015	biological_process	degradation of host chromosome by virus
C	1990238	molecular_function	double-stranded DNA endonuclease activity
D	0003677	molecular_function	DNA binding
D	0004518	molecular_function	nuclease activity
D	0004519	molecular_function	endonuclease activity
D	0008821	molecular_function	crossover junction DNA endonuclease activity
D	0008833	molecular_function	deoxyribonuclease IV (phage-T4-induced) activity
D	0015074	biological_process	DNA integration
D	0016032	biological_process	viral process
D	0016787	molecular_function	hydrolase activity
D	0039657	biological_process	symbiont-mediated suppression of host gene expression
D	0099015	biological_process	degradation of host chromosome by virus
D	1990238	molecular_function	double-stranded DNA endonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 1001

Chain	Residue
A	THR66
A	LYS67
B	SER17
B	LEU19
B	GLU20
B	HOH1012

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1002

Chain	Residue
B	GLY68
A	SER17
A	GLU20
B	THR66

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 1004

Chain	Residue
C	SER17
D	THR66
D	GLY68
D	HOH166

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