1M0D
Crystal Structure of Bacteriophage T7 Endonuclease I with a Wild-Type Active Site and Bound Manganese Ions
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0008821 | molecular_function | crossover junction DNA endonuclease activity |
| A | 0008833 | molecular_function | deoxyribonuclease IV (phage-T4-induced) activity |
| A | 0015074 | biological_process | DNA integration |
| A | 0016032 | biological_process | viral process |
| A | 0039657 | biological_process | symbiont-mediated suppression of host gene expression |
| A | 0099015 | biological_process | degradation of host chromosome by virus |
| A | 1990238 | molecular_function | double-stranded DNA endonuclease activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0008821 | molecular_function | crossover junction DNA endonuclease activity |
| B | 0008833 | molecular_function | deoxyribonuclease IV (phage-T4-induced) activity |
| B | 0015074 | biological_process | DNA integration |
| B | 0016032 | biological_process | viral process |
| B | 0039657 | biological_process | symbiont-mediated suppression of host gene expression |
| B | 0099015 | biological_process | degradation of host chromosome by virus |
| B | 1990238 | molecular_function | double-stranded DNA endonuclease activity |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004519 | molecular_function | endonuclease activity |
| C | 0008821 | molecular_function | crossover junction DNA endonuclease activity |
| C | 0008833 | molecular_function | deoxyribonuclease IV (phage-T4-induced) activity |
| C | 0015074 | biological_process | DNA integration |
| C | 0016032 | biological_process | viral process |
| C | 0039657 | biological_process | symbiont-mediated suppression of host gene expression |
| C | 0099015 | biological_process | degradation of host chromosome by virus |
| C | 1990238 | molecular_function | double-stranded DNA endonuclease activity |
| D | 0003677 | molecular_function | DNA binding |
| D | 0004519 | molecular_function | endonuclease activity |
| D | 0008821 | molecular_function | crossover junction DNA endonuclease activity |
| D | 0008833 | molecular_function | deoxyribonuclease IV (phage-T4-induced) activity |
| D | 0015074 | biological_process | DNA integration |
| D | 0016032 | biological_process | viral process |
| D | 0039657 | biological_process | symbiont-mediated suppression of host gene expression |
| D | 0099015 | biological_process | degradation of host chromosome by virus |
| D | 1990238 | molecular_function | double-stranded DNA endonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN A 1 |
| Chain | Residue |
| A | MN2 |
| A | ASP55 |
| A | GLU65 |
| A | THR66 |
| A | HOH1002 |
| A | HOH1003 |
| B | HOH1003 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MN A 2 |
| Chain | Residue |
| A | HOH1002 |
| A | HOH1004 |
| A | HOH1005 |
| B | GLU37 |
| B | HOH1004 |
| B | HOH1005 |
| A | MN1 |
| A | ASP55 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN B 3 |
| Chain | Residue |
| A | HOH1006 |
| B | MN4 |
| B | ASP55 |
| B | GLU65 |
| B | THR66 |
| B | HOH1006 |
| B | HOH1007 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN B 4 |
| Chain | Residue |
| A | GLU37 |
| A | HOH1007 |
| A | HOH1008 |
| B | MN3 |
| B | ASP55 |
| B | HOH1006 |
| B | HOH1008 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN C 5 |
| Chain | Residue |
| C | MN6 |
| C | ASP55 |
| C | GLU65 |
| C | THR66 |
| C | HOH1004 |
| C | HOH1005 |
| C | HOH1006 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN C 6 |
| Chain | Residue |
| C | MN5 |
| C | ASP55 |
| C | HOH1004 |
| C | HOH1007 |
| C | HOH1008 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN D 7 |
| Chain | Residue |
| C | HOH1009 |
| D | MN8 |
| D | ASP55 |
| D | GLU65 |
| D | THR66 |
| D | HOH1005 |
| D | HOH1006 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN D 8 |
| Chain | Residue |
| C | HOH1010 |
| C | HOH1011 |
| D | MN7 |
| D | ASP55 |
| D | HOH1005 |
| D | HOH1007 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | LYS67 |
| A | GLY68 |
| A | HOH1003 |
| A | HOH1062 |
| B | SER17 |
| B | HOH1003 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1002 |
| Chain | Residue |
| A | SER17 |
| A | HOH1006 |
| B | LYS67 |
| B | GLY68 |
| B | HOH1007 |
| B | HOH1051 |
| B | HOH1146 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1003 |
| Chain | Residue |
| C | THR66 |
| C | LYS67 |
| C | GLY68 |
| C | HOH1005 |
| C | HOH1006 |
| D | SER17 |
| site_id | BC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1004 |
| Chain | Residue |
| C | SER17 |
| C | HOH1009 |
| D | LYS67 |
| D | GLY68 |
| D | HOH1006 |
| D | HOH1032 |
| D | HOH1127 |
| D | HOH1142 |
| D | HOH1147 |
