1LVW
Crystal structure of glucose-1-phosphate thymidylyltransferase, RmlA, complex with dTDP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| B | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| C | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| D | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 4001 |
| Chain | Residue |
| A | THR198 |
| A | ASN201 |
| A | HOH1053 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 4002 |
| Chain | Residue |
| B | THR198 |
| B | ASN201 |
| B | HOH1151 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 4003 |
| Chain | Residue |
| C | HOH1250 |
| C | THR198 |
| C | ASN201 |
| C | HOH1247 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 4004 |
| Chain | Residue |
| D | THR198 |
| D | ASN201 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 4005 |
| Chain | Residue |
| A | LYS165 |
| A | HOH1444 |
| B | ASP149 |
| B | SER150 |
| C | HIS291 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 5001 |
| Chain | Residue |
| A | SER199 |
| A | ARG206 |
| A | HOH1176 |
| A | HOH1302 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 D 5002 |
| Chain | Residue |
| C | THR262 |
| C | ARG263 |
| C | GLU264 |
| C | HOH1727 |
| D | TYR256 |
| D | ARG263 |
| D | HOH1202 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE TYD A 3001 |
| Chain | Residue |
| A | LEU6 |
| A | GLY8 |
| A | LYS23 |
| A | GLN24 |
| A | GLN80 |
| A | PRO83 |
| A | ARG84 |
| A | GLY85 |
| A | LEU106 |
| A | GLY107 |
| A | ASP108 |
| A | GLU194 |
| A | HOH1618 |
| A | HOH1619 |
| A | GOL2007 |
| site_id | AC9 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE TYD A 3002 |
| Chain | Residue |
| A | LEU43 |
| A | TYR112 |
| A | GLY113 |
| A | HIS114 |
| A | ARG115 |
| A | PHE116 |
| A | SER117 |
| A | ILE248 |
| A | ALA249 |
| A | GLU253 |
| A | ILE254 |
| A | HOH1007 |
| A | HOH1023 |
| A | HOH1026 |
| A | HOH1035 |
| A | HOH1048 |
| A | HOH1190 |
| A | HOH1315 |
| C | ARG217 |
| site_id | BC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE TYD B 3003 |
| Chain | Residue |
| B | LEU6 |
| B | GLY8 |
| B | GLY9 |
| B | LYS23 |
| B | GLN24 |
| B | GLN80 |
| B | PRO83 |
| B | ARG84 |
| B | GLY85 |
| B | LEU106 |
| B | ASP108 |
| B | GLU194 |
| B | HOH1683 |
| site_id | BC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE TYD B 3004 |
| Chain | Residue |
| B | LEU43 |
| B | TYR112 |
| B | GLY113 |
| B | HIS114 |
| B | ARG115 |
| B | PHE116 |
| B | SER117 |
| B | ILE248 |
| B | ALA249 |
| B | GLU253 |
| B | ILE254 |
| B | HOH1002 |
| B | HOH1013 |
| B | HOH1043 |
| B | HOH1055 |
| B | HOH1102 |
| B | HOH1129 |
| B | HOH1570 |
| D | ARG217 |
| site_id | BC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE TYD C 3005 |
| Chain | Residue |
| C | GLN80 |
| C | PRO83 |
| C | ARG84 |
| C | GLY85 |
| C | LEU106 |
| C | ASP108 |
| C | GOL2003 |
| C | LEU6 |
| C | GLY8 |
| C | GLY9 |
| C | LYS23 |
| C | GLN24 |
| site_id | BC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE TYD C 3006 |
| Chain | Residue |
| A | ARG217 |
| A | HOH1078 |
| C | LEU43 |
| C | TYR112 |
| C | GLY113 |
| C | HIS114 |
| C | ARG115 |
| C | PHE116 |
| C | SER117 |
| C | ILE248 |
| C | ALA249 |
| C | ILE254 |
| C | HOH1011 |
| C | HOH1018 |
| C | HOH1069 |
| C | HOH1081 |
| C | HOH1091 |
| C | HOH1093 |
| C | HOH1405 |
| site_id | BC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE TYD D 3007 |
| Chain | Residue |
| D | LEU6 |
| D | GLY8 |
| D | GLY9 |
| D | LYS23 |
| D | GLN24 |
| D | GLN80 |
| D | PRO83 |
| D | ARG84 |
| D | GLY85 |
| D | LEU106 |
| D | ASP108 |
| D | GOL2004 |
| site_id | BC6 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE TYD D 3008 |
| Chain | Residue |
| B | ARG217 |
| B | HOH1107 |
| D | LEU43 |
| D | TYR112 |
| D | GLY113 |
| D | HIS114 |
| D | ARG115 |
| D | PHE116 |
| D | SER117 |
| D | ILE248 |
| D | ALA249 |
| D | ILE254 |
| D | HOH1037 |
| D | HOH1060 |
| D | HOH1075 |
| D | HOH1089 |
| D | HOH1217 |
| D | HOH1427 |
| D | HOH1645 |
| site_id | BC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL C 2001 |
| Chain | Residue |
| A | LYS242 |
| A | ARG243 |
| A | GLY245 |
| C | ARG138 |
| C | ASP139 |
| C | HOH1178 |
| C | HOH1293 |
| C | GOL2010 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 2002 |
| Chain | Residue |
| B | ARG138 |
| B | ASP139 |
| B | HOH1307 |
| B | HOH1697 |
| D | LYS242 |
| D | ARG243 |
| D | GLY245 |
| site_id | BC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL C 2003 |
| Chain | Residue |
| C | LYS23 |
| C | ASP108 |
| C | LEU222 |
| C | ASP223 |
| C | THR224 |
| C | GLY225 |
| C | GOL2010 |
| C | TYD3005 |
| site_id | CC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL D 2004 |
| Chain | Residue |
| B | GOL2011 |
| D | LYS23 |
| D | ASP108 |
| D | LEU222 |
| D | ASP223 |
| D | THR224 |
| D | GLY225 |
| D | TYD3007 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 2005 |
| Chain | Residue |
| A | ARG138 |
| A | ASP139 |
| A | PHE143 |
| A | HOH1294 |
| C | LYS242 |
| C | ARG243 |
| C | GLY245 |
| site_id | CC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL D 2006 |
| Chain | Residue |
| B | LYS242 |
| B | ARG243 |
| B | GLY245 |
| D | ARG138 |
| D | ASP139 |
| D | PHE143 |
| D | HOH1297 |
| D | HOH1536 |
| site_id | CC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 2007 |
| Chain | Residue |
| A | LYS23 |
| A | ASP108 |
| A | LEU222 |
| A | ASP223 |
| A | THR224 |
| A | GLY225 |
| A | HOH1015 |
| A | HOH1206 |
| A | TYD3001 |
| C | HOH1591 |
| site_id | CC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 2008 |
| Chain | Residue |
| B | GLU151 |
| B | GLY152 |
| B | VAL212 |
| B | GLU213 |
| B | HOH1295 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 2009 |
| Chain | Residue |
| A | GLU147 |
| A | PHE148 |
| A | LYS165 |
| A | SER166 |
| A | HOH1034 |
| site_id | CC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL C 2010 |
| Chain | Residue |
| A | ARG243 |
| C | PHE143 |
| C | TRP221 |
| C | LEU222 |
| C | ASP223 |
| C | HOH1178 |
| C | HOH1544 |
| C | GOL2001 |
| C | GOL2003 |
| site_id | CC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 2011 |
| Chain | Residue |
| B | ARG243 |
| B | HOH1700 |
| D | TRP221 |
| D | LEU222 |
| D | HOH1536 |
| D | GOL2004 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hv9 |
| Chain | Residue | Details |
| A | ARG13 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hv9 |
| Chain | Residue | Details |
| B | ARG13 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hv9 |
| Chain | Residue | Details |
| C | ARG13 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hv9 |
| Chain | Residue | Details |
| D | ARG13 |
