1LV0
Crystal structure of the Rab effector guanine nucleotide dissociation inhibitor (GDI) in complex with a geranylgeranyl (GG) peptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005092 | molecular_function | GDP-dissociation inhibitor activity |
| A | 0005093 | molecular_function | Rab GDP-dissociation inhibitor activity |
| A | 0005096 | molecular_function | GTPase activator activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005829 | cellular_component | cytosol |
| A | 0007264 | biological_process | small GTPase-mediated signal transduction |
| A | 0015031 | biological_process | protein transport |
| A | 0016192 | biological_process | vesicle-mediated transport |
| A | 0032482 | biological_process | Rab protein signal transduction |
| A | 0050771 | biological_process | negative regulation of axonogenesis |
| A | 0090315 | biological_process | negative regulation of protein targeting to membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | MET82 |
| A | GLY85 |
| A | GLN86 |
| A | LEU87 |
| A | GLU411 |
| A | CYS414 |
| A | HOH538 |
| A | HOH560 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1002 |
| Chain | Residue |
| A | LYS118 |
| A | ASN130 |
| A | HOH523 |
| A | TYR117 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1003 |
| Chain | Residue |
| A | TYR192 |
| A | ARG193 |
| A | THR194 |
| A | HOH505 |
| A | HOH624 |
| A | HOH653 |
| A | HOH736 |
| A | HOH776 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GER A 1000 |
| Chain | Residue |
| A | VAL25 |
| A | TYR93 |
| A | ASP430 |
| A | PHE431 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P50396 |
| Chain | Residue | Details |
| A | SER427 |
