1LTK

CRYSTAL STRUCTURE OF PHOSPHOGLYCERATE KINASE FROM PLASMODIUM FALCIPARUM, IN THE OPEN CONFORMATION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004618	molecular_function	phosphoglycerate kinase activity
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006094	biological_process	gluconeogenesis
A	0006096	biological_process	glycolytic process
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0043531	molecular_function	ADP binding
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0004618	molecular_function	phosphoglycerate kinase activity
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0006094	biological_process	gluconeogenesis
B	0006096	biological_process	glycolytic process
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0043531	molecular_function	ADP binding
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0004618	molecular_function	phosphoglycerate kinase activity
C	0005524	molecular_function	ATP binding
C	0005829	cellular_component	cytosol
C	0006094	biological_process	gluconeogenesis
C	0006096	biological_process	glycolytic process
C	0016301	molecular_function	kinase activity
C	0016740	molecular_function	transferase activity
C	0043531	molecular_function	ADP binding
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 604

Chain	Residue
C	ASN26
C	ARG66
C	ARG122
C	LYS138
C	ARG170

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 605

Chain	Residue
A	HIS63
A	ARG66
A	ARG122
A	ARG170

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 606

Chain	Residue
B	ASN26
B	HIS63
B	ARG66
B	ARG122
B	ARG170

---

site_id	AC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE AMP A 501

Chain	Residue
A	GLY213
A	ALA214
A	LYS215
A	GLY237
A	GLY238
A	LEU256
A	GLY340
A	VAL341
A	GLU343
A	ASP374
B	LYS140
B	LYS143

---

site_id	AC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE AMP B 502

Chain	Residue
A	LYS143
B	GLY213
B	ALA214
B	LYS215
B	LYS219
B	GLY237
B	GLY238
B	LEU313
B	GLY340
B	VAL341
B	GLU343
B	ASP374

---

site_id	AC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE AMP C 503

Chain	Residue
C	LYS140
C	LYS143
C	GLY213
C	ALA214
C	LYS215
C	GLY237
C	GLY238
C	LEU256
C	GLY340
C	GLU343
C	ASP374

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 614

Chain	Residue
A	ASN72
A	LYS74
A	TYR75
B	LYS74

---

Functional Information from PROSITE/UniProt

site_id	PS00111
Number of Residues	11
Details	PGLYCERATE_KINASE Phosphoglycerate kinase signature. KVLVRvDfNVP

Chain	Residue	Details
A	LYS18-PRO28

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	39
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P00558","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	39
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q7SIB7","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 13pk

Chain	Residue	Details
A	LYS215
A	ARG39
A	GLY373
A	GLY396

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 13pk

Chain	Residue	Details
B	LYS215
B	ARG39
B	GLY373
B	GLY396

---

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 13pk

Chain	Residue	Details
C	LYS215
C	ARG39
C	GLY373
C	GLY396

---