1LRW
Crystal structure of methanol dehydrogenase from P. denitrificans
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0016020 | cellular_component | membrane |
| A | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| A | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| B | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| B | 0015945 | biological_process | methanol metabolic process |
| B | 0015946 | biological_process | methanol oxidation |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0052933 | molecular_function | alcohol dehydrogenase (cytochrome c(L)) activity |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0016020 | cellular_component | membrane |
| C | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| C | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| D | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| D | 0015945 | biological_process | methanol metabolic process |
| D | 0015946 | biological_process | methanol oxidation |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0042597 | cellular_component | periplasmic space |
| D | 0052933 | molecular_function | alcohol dehydrogenase (cytochrome c(L)) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 702 |
| Chain | Residue |
| A | GLU177 |
| A | ASN261 |
| A | ASP303 |
| A | PQQ701 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA C 702 |
| Chain | Residue |
| C | GLU177 |
| C | ASN261 |
| C | PQQ701 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE PQQ A 701 |
| Chain | Residue |
| A | CYS104 |
| A | VAL107 |
| A | ARG109 |
| A | THR159 |
| A | SER174 |
| A | GLY175 |
| A | ALA176 |
| A | GLU177 |
| A | THR241 |
| A | TRP243 |
| A | ARG331 |
| A | TRP476 |
| A | GLY539 |
| A | TRP540 |
| A | CA702 |
| A | HOH726 |
| A | HOH820 |
| A | GLU55 |
| A | CYS103 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE PQQ C 701 |
| Chain | Residue |
| C | GLU55 |
| C | CYS103 |
| C | ARG109 |
| C | THR159 |
| C | SER174 |
| C | GLY175 |
| C | ALA176 |
| C | GLU177 |
| C | THR241 |
| C | TRP243 |
| C | ASN261 |
| C | ARG331 |
| C | TRP476 |
| C | GLY539 |
| C | TRP540 |
| C | CA702 |
| C | HOH771 |
| C | HOH772 |
| C | HOH863 |
Functional Information from PROSITE/UniProt
| site_id | PS00363 |
| Number of Residues | 29 |
| Details | BACTERIAL_PQQ_1 Bacterial quinoprotein dehydrogenases signature 1. NWvmtGRdynaqnYSemtdINkeNVkqLR |
| Chain | Residue | Details |
| A | ASN13-ARG41 |
| site_id | PS00364 |
| Number of Residues | 22 |
| Details | BACTERIAL_PQQ_2 Bacterial quinoprotein dehydrogenases signature 2. WgwyaYDpevDLFYYgsGnpAP |
| Chain | Residue | Details |
| A | TRP243-PRO264 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | ASP303 | |
| C | ASP303 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU177 | |
| A | ASN261 | |
| C | GLU177 | |
| C | ASN261 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1g72 |
| Chain | Residue | Details |
| A | ASP303 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1g72 |
| Chain | Residue | Details |
| C | ASP303 |
