1LOK
The 1.20 Angstrom Resolution Crystal Structure of the Aminopeptidase from Aeromonas proteolytica Complexed with Tris: A Tale of Buffer Inhibition
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 901 |
| Chain | Residue |
| A | ASP117 |
| A | GLU152 |
| A | HIS256 |
| A | TRS800 |
| A | ZN902 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN A 902 |
| Chain | Residue |
| A | ASP179 |
| A | TRS800 |
| A | ZN901 |
| A | HIS97 |
| A | ASP117 |
| A | GLU151 |
| A | GLU152 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 903 |
| Chain | Residue |
| A | TYR218 |
| A | HOH1024 |
| A | HOH1035 |
| A | HOH1043 |
| A | HOH1045 |
| A | HOH1095 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SCN A 1973 |
| Chain | Residue |
| A | ASN171 |
| A | VAL172 |
| A | TYR238 |
| A | PRO239 |
| A | HOH1192 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE TRS A 800 |
| Chain | Residue |
| A | HIS97 |
| A | ASP117 |
| A | GLU151 |
| A | GLU152 |
| A | ASP179 |
| A | MET180 |
| A | TYR225 |
| A | CYS227 |
| A | HIS256 |
| A | ZN901 |
| A | ZN902 |
| A | HOH1116 |
| A | HOH1293 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10413478, ECO:0000269|PubMed:11401547, ECO:0000269|PubMed:8087555, ECO:0000269|PubMed:8647077, ECO:0007744|PDB:1AMP, ECO:0007744|PDB:1CP6, ECO:0007744|PDB:1FT7, ECO:0007744|PDB:1IGB, ECO:0007744|PDB:1LOK, ECO:0007744|PDB:1RTQ, ECO:0007744|PDB:1TXR, ECO:0007744|PDB:1XRY, ECO:0007744|PDB:2ANP, ECO:0007744|PDB:2DEA, ECO:0007744|PDB:2IQ6, ECO:0007744|PDB:2NYQ, ECO:0007744|PDB:3B35, ECO:0007744|PDB:3B3C, ECO:0007744|PDB:3B3S, ECO:0007744|PDB:3B3T, ECO:0007744|PDB:3B3V, ECO:0007744|PDB:3B3W, ECO:0007744|PDB:3B7I, ECO:0007744|PDB:3FH4, ECO:0007744|PDB:3VH9 |
| Chain | Residue | Details |
| A | HIS97 | |
| A | ASP117 | |
| A | GLU152 | |
| A | ASP179 | |
| A | HIS256 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 167 |
| Chain | Residue | Details |
| A | HIS97 | metal ligand |
| A | ASP117 | metal ligand |
| A | GLU151 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | GLU152 | metal ligand |
| A | ASP179 | metal ligand |
| A | HIS256 | metal ligand |
