1LLM

Crystal Structure of a Zif23-GCN4 Chimera Bound to DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006355	biological_process	regulation of DNA-templated transcription
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 301

Chain	Residue
C	CYS106
C	CYS109
C	HIS122
C	HIS126

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 302

Chain	Residue
C	CYS134
C	CYS137
C	HIS150
C	HIS155

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 303

Chain	Residue
D	CYS209
D	HIS222
D	HIS226
D	CYS206

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 304

Chain	Residue
D	CYS234
D	CYS237
D	HIS250
D	HIS255

---

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	21
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cri..CmrnFsrsdhlttHirt..H

Chain	Residue	Details
C	CYS106-HIS126
C	CYS134-HIS155

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	42
Details	Region: {"description":"Leucine-zipper","evidences":[{"source":"PROSITE-ProRule","id":"PRU00978","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"1473154","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	44
Details	Zinc finger: {"description":"C2H2-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	10
Details	Site: {"description":"Interaction with DNA","evidences":[{"source":"PubMed","id":"2028256","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8939742","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1AAY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ZAA","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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