1LFU

NMR Solution Structure of the Extended PBX Homeodomain Bound to DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
P	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
P	0003677	molecular_function	DNA binding
P	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. LAkkSgITvsQVSNWFgNkriryK

Chain	Residue	Details
P	LEU34-LYS57

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	62
Details	DNA binding: {"description":"Homeobox; TALE-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00108","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Site: {"description":"Required for binding to the NFIL3 promoter","evidences":[{"source":"PubMed","id":"32190943","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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