1LFU

NMR Solution Structure of the Extended PBX Homeodomain Bound to DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
P	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
P	0003677	molecular_function	DNA binding
P	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. LAkkSgITvsQVSNWFgNkriryK

Chain	Residue	Details
P	LEU34-LYS57

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	62
Details	DNA_BIND: Homeobox; TALE-type => ECO:0000255|PROSITE-ProRule:PRU00108

Chain	Residue	Details
P	ALA1-ILE60

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Required for binding to the NFIL3 promoter => ECO:0000269|PubMed:32190943

Chain	Residue	Details
P	ASN51

---