1L7V

Bacterial ABC Transporter Involved in B12 Uptake

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0015420	molecular_function	ABC-type vitamin B12 transporter activity
A	0015889	biological_process	cobalamin transport
A	0016020	cellular_component	membrane
A	0022857	molecular_function	transmembrane transporter activity
A	0035461	biological_process	vitamin transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055085	biological_process	transmembrane transport
A	0090482	molecular_function	vitamin transmembrane transporter activity
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0015420	molecular_function	ABC-type vitamin B12 transporter activity
B	0015889	biological_process	cobalamin transport
B	0016020	cellular_component	membrane
B	0022857	molecular_function	transmembrane transporter activity
B	0035461	biological_process	vitamin transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0055085	biological_process	transmembrane transport
B	0090482	molecular_function	vitamin transmembrane transporter activity
C	0000166	molecular_function	nucleotide binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0015420	molecular_function	ABC-type vitamin B12 transporter activity
C	0015889	biological_process	cobalamin transport
C	0016020	cellular_component	membrane
C	0016887	molecular_function	ATP hydrolysis activity
C	0019898	cellular_component	extrinsic component of membrane
C	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
C	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
C	0055085	biological_process	transmembrane transport
D	0000166	molecular_function	nucleotide binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005886	cellular_component	plasma membrane
D	0015420	molecular_function	ABC-type vitamin B12 transporter activity
D	0015889	biological_process	cobalamin transport
D	0016020	cellular_component	membrane
D	0016887	molecular_function	ATP hydrolysis activity
D	0019898	cellular_component	extrinsic component of membrane
D	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
D	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
D	0055085	biological_process	transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE V4O C 250

Chain	Residue
C	PRO34
C	ASN35
C	GLY36
C	ALA37
C	GLY38
C	LYS39
C	SER40
C	THR41

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE V4O D 250

Chain	Residue
D	ASN35
D	GLY36
D	ALA37
D	GLY38
D	LYS39
D	SER40
D	THR41
D	PRO34

---

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGEWQRVRLAAVV

Chain	Residue	Details
C	LEU127-VAL141

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	64
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"15919996","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	36
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"15919996","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	28
Details	Transmembrane: {"description":"Helical; Name=3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	48
Details	Transmembrane: {"description":"Helical; Name=4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	18
Details	Transmembrane: {"description":"Helical; Name=8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01005","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---