Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 500 |
| Chain | Residue |
| A | CYS99 |
| A | HIS401 |
| A | HIS405 |
| A | HIS411 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 501 |
| Chain | Residue |
| A | HIS175 |
| A | ASP177 |
| A | HIS190 |
| A | HIS203 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 502 |
| Chain | Residue |
| A | GLY183 |
| A | GLY186 |
| A | LEU187 |
| A | ASP205 |
| A | GLU208 |
| A | ASP182 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 503 |
| Chain | Residue |
| A | ASP131 |
| A | ASP206 |
| A | GLU208 |
| A | HOH1054 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 504 |
| Chain | Residue |
| A | ALA164 |
| A | ASP165 |
| A | GLY197 |
| A | GLN199 |
| A | ASP201 |
| A | HOH1052 |
| A | HOH1174 |
Functional Information from PROSITE/UniProt
| site_id | PS00023 |
| Number of Residues | 42 |
| Details | FN2_1 Fibronectin type-II collagen-binding domain signature. ChfPFiFegrsysaCttdgrsdglpWCsttaNYdtddrFgFC |
| Chain | Residue | Details |
| A | CYS230-CYS271 | |
| A | CYS288-CYS329 | |
| A | CYS347-CYS388 | |
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VAAHEFGHAL |
| Chain | Residue | Details |
| A | VAL398-LEU407 | |
| site_id | PS00546 |
| Number of Residues | 8 |
| Details | CYSTEINE_SWITCH Matrixins cysteine switch. PRCGvPDL |
| Chain | Residue | Details |
| A | PRO97-LEU104 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLU402 | |
| Chain | Residue | Details |
| A | CYS99 | |
| Chain | Residue | Details |
| A | ASP131 | |
| A | ASP205 | |
| A | ASP206 | |
| A | GLU208 | |
| A | ASP165 | |
| A | ASP182 | |
| A | GLY183 | |
| A | ASP185 | |
| A | LEU187 | |
| A | GLY197 | |
| A | GLN199 | |
| A | ASP201 | |
| Chain | Residue | Details |
| A | HIS175 | |
| A | ASP177 | |
| A | HIS190 | |
| A | HIS203 | |
| A | HIS401 | |
| A | HIS405 | |
| A | HIS411 | |
| Chain | Residue | Details |
| A | GLU59 | |
| A | ARG106 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN38 | |
| A | ASN120 | |
| A | ASN127 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | MET419 | |
| A | GLU402 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | ARG221 | |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | GLU402 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | ALA228 | |
