1KZN

Crystal Structure of E. coli 24kDa Domain in Complex with Clorobiocin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0006265	biological_process	DNA topological change

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE CBN A 1

Chain	Residue
A	ARG22
A	PRO79
A	ILE90
A	HIS95
A	ARG136
A	THR165
A	HOH1122
A	HOH1154
A	HOH1160
A	HOH1172
A	HOH1176
A	TYR26
A	ASN46
A	GLU50
A	VAL71
A	ASP73
A	ARG76
A	GLY77
A	ILE78

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor (ATPase activity) => ECO:0000305|PubMed:10734094, ECO:0000305|PubMed:8248233

Chain	Residue	Details
A	VAL43

---

site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:10734094, ECO:0000269|PubMed:25202966, ECO:0000269|PubMed:25849408

Chain	Residue	Details
A	ALA47
A	ASP74
A	LYS103
A	LYS110
A	HIS116

---

site_id	SWS_FT_FI3
Number of Residues	7
Details	BINDING: BINDING => ECO:0000269|PubMed:25849408

Chain	Residue	Details
A	MET91
A	LEU94
A	GLY101
A	PHE104
A	ASP106
A	VAL118
A	VAL122

---