1KXU
CYCLIN H, A POSITIVE REGULATORY SUBUNIT OF CDK ACTIVATING KINASE
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000307 | cellular_component | cyclin-dependent protein kinase holoenzyme complex |
A | 0000439 | cellular_component | transcription factor TFIIH core complex |
A | 0005515 | molecular_function | protein binding |
A | 0005634 | cellular_component | nucleus |
A | 0005654 | cellular_component | nucleoplasm |
A | 0005675 | cellular_component | transcription factor TFIIH holo complex |
A | 0006351 | biological_process | DNA-templated transcription |
A | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
A | 0006367 | biological_process | transcription initiation at RNA polymerase II promoter |
A | 0016251 | molecular_function | RNA polymerase II general transcription initiation factor activity |
A | 0016538 | molecular_function | cyclin-dependent protein serine/threonine kinase regulator activity |
A | 0050821 | biological_process | protein stabilization |
A | 0070516 | cellular_component | CAK-ERCC2 complex |
A | 0070985 | cellular_component | transcription factor TFIIK complex |
A | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | MOD_RES: Phosphoserine; by CDK8 => ECO:0000269|PubMed:10993082 |
Chain | Residue | Details |
A | SER5 | |
A | SER304 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
A | SER132 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19369195, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
A | THR315 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:20068231 |
Chain | Residue | Details |
A | SER322 |