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1KS9

Ketopantoate Reductase from Escherichia coli

Functional Information from GO Data
ChainGOidnamespacecontents
A0005737cellular_componentcytoplasm
A0008677molecular_function2-dehydropantoate 2-reductase activity
A0015940biological_processpantothenate biosynthetic process
A0016491molecular_functionoxidoreductase activity
A0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A0050661molecular_functionNADP binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Proton donor => ECO:0000305|PubMed:11123955
ChainResidueDetails
ALYS176

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:15966718, ECO:0000269|PubMed:17229734
ChainResidueDetails
AGLY7
AARG31
AALA122
AGLU256

site_idSWS_FT_FI3
Number of Residues6
DetailsBINDING: BINDING => ECO:0000269|PubMed:17229734
ChainResidueDetails
AASN98
AASN180
AASN184
AASN194
AASN241
ASER244

Catalytic Information from CSA
site_idMCSA1
Number of Residues1
DetailsM-CSA 721
ChainResidueDetails
ALYS176proton acceptor, proton donor

226707

PDB entries from 2024-10-30

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