1KO0

Crystal Structure of a D,L-lysine complex of diaminopimelate decarboxylase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005515	molecular_function	protein binding
A	0008836	molecular_function	diaminopimelate decarboxylase activity
A	0009085	biological_process	lysine biosynthetic process
A	0009089	biological_process	lysine biosynthetic process via diaminopimelate
A	0016830	molecular_function	carbon-carbon lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0030170	molecular_function	pyridoxal phosphate binding
A	0042803	molecular_function	protein homodimerization activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE PLP A 540

Chain	Residue
A	ALA52
A	TYR378
A	LYS541
A	DLY542
A	HOH579
A	HOH582
A	HOH666
A	HOH870
A	LYS54
A	HIS191
A	GLY226
A	GLY227
A	GLU268
A	GLY270
A	ARG271
A	CYS342

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE LYS A 541

Chain	Residue
A	LYS54
A	HIS191
A	ARG271
A	ARG307
A	TYR311
A	CYS342
A	GLU343
A	TYR378
A	MET382
A	TYR386
A	PLP540

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE DLY A 542

Chain	Residue
A	LYS54
A	THR157
A	HIS191
A	TYR311
A	CYS342
A	GLU343
A	SER344
A	TYR378
A	TYR386
A	PLP540
A	HOH887

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Functional Information from PROSITE/UniProt

site_id	PS00878
Number of Residues	19
Details	ODR_DC_2_1 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. FAqKACsnihILrlMreqG

Chain	Residue	Details
A	PHE51-GLY69

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site_id	PS00879
Number of Residues	14
Details	ODR_DC_2_2 Orn/DAP/Arg decarboxylases family 2 signature 2. Gqd....LqAISAGGGLS

Chain	Residue	Details
A	GLY216-SER229

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_02120

Chain	Residue	Details
A	CYS342

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site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000305|Ref.10

Chain	Residue	Details
A	HIS191
A	ARG271
A	ARG307
A	TYR311
A	GLU343

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|Ref.10

Chain	Residue	Details
A	GLY227

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site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_02120, ECO:0000269|Ref.10

Chain	Residue	Details
A	GLU268

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_02120

Chain	Residue	Details
A	TYR378

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site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000269|Ref.10

Chain	Residue	Details
A	LYS54

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