1KL9

Crystal structure of the N-terminal segment of Human eukaryotic initiation factor 2alpha

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
A	0003743	molecular_function	translation initiation factor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 501

Chain	Residue
A	GLU42
A	HIS154
A	ASP158
A	HOH592

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 502

Chain	Residue
A	HIS10
A	HIS10
A	HOH587
A	HOH596
A	HOH596

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 503

Chain	Residue
A	HIS10
A	LYS11
A	PHE12
A	LYS77
A	LYS142

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 504

Chain	Residue
A	HIS113
A	GLU119
A	HOH584

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine; by HRI => ECO:0000250|UniProtKB:P83268

Chain	Residue	Details
A	GLU49

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	ARG52

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	TYR141

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	ASP158

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