Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0020037 | molecular_function | heme binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM A 760 |
| Chain | Residue |
| A | LEU36 |
| A | HIS66 |
| A | VAL70 |
| A | ILE71 |
| A | TYR97 |
| A | GLN139 |
| A | TYR143 |
| A | ALA198 |
| A | LEU199 |
| A | LEU230 |
| A | LYS296 |
| A | PHE39 |
| A | HOH797 |
| A | HOH807 |
| A | HOH858 |
| A | HOH871 |
| A | HIS43 |
| A | PRO44 |
| A | GLY45 |
| A | VAL49 |
| A | VAL58 |
| A | ILE61 |
| A | PHE62 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE FMN A 770 |
| Chain | Residue |
| A | TYR143 |
| A | TYR144 |
| A | SER195 |
| A | ALA196 |
| A | THR197 |
| A | ALA198 |
| A | SER228 |
| A | GLN252 |
| A | TYR254 |
| A | THR280 |
| A | LYS349 |
| A | SER371 |
| A | HIS373 |
| A | GLY374 |
| A | ARG376 |
| A | ASP409 |
| A | GLY410 |
| A | GLY411 |
| A | ARG413 |
| A | GLY432 |
| A | ARG433 |
| A | LEU436 |
| A | HOH771 |
| A | HOH797 |
| A | HOH814 |
| site_id | AC3 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE FMN B 870 |
| Chain | Residue |
| B | TYR143 |
| B | TYR144 |
| B | SER195 |
| B | ALA196 |
| B | THR197 |
| B | ALA198 |
| B | SER228 |
| B | GLN252 |
| B | TYR254 |
| B | THR280 |
| B | LYS349 |
| B | SER371 |
| B | HIS373 |
| B | GLY374 |
| B | ARG376 |
| B | ASP409 |
| B | GLY410 |
| B | GLY411 |
| B | ARG413 |
| B | LEU431 |
| B | GLY432 |
| B | ARG433 |
| B | LEU436 |
| B | PYR800 |
| B | HOH901 |
| B | HOH908 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PYR B 800 |
| Chain | Residue |
| B | TYR143 |
| B | TYR254 |
| B | HIS373 |
| B | ARG376 |
| B | FMN870 |
| B | HOH1020 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD A 701 |
| Chain | Residue |
| A | ARG259 |
| A | ASP263 |
| A | ASP334 |
| A | GLU337 |
| A | LYS341 |
| A | HOH937 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD A 702 |
| Chain | Residue |
| A | ARG353 |
| A | GLU355 |
| A | LYS359 |
| A | HOH948 |
| B | LYS169 |
| B | ASP476 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MPD A 703 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD A 704 |
| Chain | Residue |
| A | GLU355 |
| A | GLU390 |
| A | ILE394 |
| A | ARG398 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD B 801 |
| Chain | Residue |
| B | ASP263 |
| B | ASP334 |
| B | LEU338 |
| B | ARG259 |
| B | THR262 |
Functional Information from PROSITE/UniProt
| site_id | PS00191 |
| Number of Residues | 8 |
| Details | CYTOCHROME_B5_1 Cytochrome b5 family, heme-binding domain signature. FLPNHPGG |
| Chain | Residue | Details |
| A | PHE39-GLY46 | |
| site_id | PS00557 |
| Number of Residues | 7 |
| Details | FMN_HYDROXY_ACID_DH_1 FMN-dependent alpha-hydroxy acid dehydrogenases active site. SNHGGRQ |
| Chain | Residue | Details |
| A | SER371-GLN377 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS373 | |
| B | HIS373 | |
| Chain | Residue | Details |
| A | HIS43 | |
| A | HIS66 | |
| B | HIS43 | |
| B | HIS66 | |
| Chain | Residue | Details |
| A | TYR97 | |
| A | ARG376 | |
| A | ASP409 | |
| A | GLY432 | |
| B | TYR97 | |
| B | TYR143 | |
| B | SER195 | |
| B | SER228 | |
| B | GLN252 | |
| B | TYR254 | |
| B | THR280 | |
| A | TYR143 | |
| B | LYS349 | |
| B | HIS373 | |
| B | ARG376 | |
| B | ASP409 | |
| B | GLY432 | |
| A | SER195 | |
| A | SER228 | |
| A | GLN252 | |
| A | TYR254 | |
| A | THR280 | |
| A | LYS349 | |
| A | HIS373 | |
| Chain | Residue | Details |
| A | GLN139 | |
| A | LYS296 | |
| B | GLN139 | |
| B | LYS296 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 102 |
| Chain | Residue | Details |
| A | TYR254 | electrostatic stabiliser, hydrogen bond donor |
| A | ASP282 | electrostatic stabiliser, hydrogen bond acceptor |
| A | HIS373 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 3 |
| Details | M-CSA 102 |
| Chain | Residue | Details |
| B | TYR254 | electrostatic stabiliser, hydrogen bond donor |
| B | ASP282 | electrostatic stabiliser, hydrogen bond acceptor |
| B | HIS373 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
