1KAO

CRYSTAL STRUCTURE OF THE SMALL G PROTEIN RAP2A WITH GDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0001934	biological_process	positive regulation of protein phosphorylation
A	0003924	molecular_function	GTPase activity
A	0003925	molecular_function	G protein activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005768	cellular_component	endosome
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0007165	biological_process	signal transduction
A	0008104	biological_process	protein localization
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0019003	molecular_function	GDP binding
A	0030033	biological_process	microvillus assembly
A	0030036	biological_process	actin cytoskeleton organization
A	0030336	biological_process	negative regulation of cell migration
A	0030496	cellular_component	midbody
A	0030659	cellular_component	cytoplasmic vesicle membrane
A	0031954	biological_process	positive regulation of protein autophosphorylation
A	0032486	biological_process	Rap protein signal transduction
A	0045184	biological_process	establishment of protein localization
A	0045198	biological_process	establishment of epithelial cell apical/basal polarity
A	0045202	cellular_component	synapse
A	0046328	biological_process	regulation of JNK cascade
A	0048814	biological_process	regulation of dendrite morphogenesis
A	0051963	biological_process	regulation of synapse assembly
A	0055037	cellular_component	recycling endosome
A	0055038	cellular_component	recycling endosome membrane
A	0071466	biological_process	cellular response to xenobiotic stimulus
A	0072659	biological_process	protein localization to plasma membrane
A	0097060	cellular_component	synaptic membrane
A	0098588	cellular_component	bounding membrane of organelle
A	0098685	cellular_component	Schaffer collateral - CA1 synapse
A	0099072	biological_process	regulation of postsynaptic membrane neurotransmitter receptor levels

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 168

Chain	Residue
A	SER17
A	GDP170
A	HOH171
A	HOH172
A	HOH173
A	HOH174

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 169

Chain	Residue
A	HOH240
A	ASP38
A	HOH227
A	HOH239

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site_id	AC3
Number of Residues	21
Details	BINDING SITE FOR RESIDUE GDP A 170

Chain	Residue
A	GLY13
A	VAL14
A	GLY15
A	LYS16
A	SER17
A	ALA18
A	PHE28
A	ILE29
A	GLU30
A	LYS31
A	ASN116
A	LYS117
A	ASP119
A	LEU120
A	SER146
A	ALA147
A	MG168
A	HOH171
A	HOH172
A	HOH173
A	HOH179

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	GLY10
A	ASP57
A	ASN116

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: (Microbial infection) O-linked (Glc) threonine; by C.difficile toxin TcdA, and by P.sordellii toxin TcsL => ECO:0000269|PubMed:22267739, ECO:0000269|PubMed:8626586

Chain	Residue	Details
A	THR35

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	THR61

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