1KA7
SAP/SH2D1A bound to peptide n-Y-c
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002250 | biological_process | adaptive immune response |
| A | 0002376 | biological_process | immune system process |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006959 | biological_process | humoral immune response |
| A | 0006968 | biological_process | cellular defense response |
| A | 0007267 | biological_process | cell-cell signaling |
| A | 0030101 | biological_process | natural killer cell activation |
| A | 0030674 | molecular_function | protein-macromolecule adaptor activity |
| A | 0042267 | biological_process | natural killer cell mediated cytotoxicity |
| A | 0045087 | biological_process | innate immune response |
| A | 0045954 | biological_process | positive regulation of natural killer cell mediated cytotoxicity |
| A | 0050776 | biological_process | regulation of immune response |
| A | 0050860 | biological_process | negative regulation of T cell receptor signaling pathway |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 98 |
| Details | Domain: {"description":"SH2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00191","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 25 |
| Details | Region: {"description":"Interaction with FYN SH3 domain","evidences":[{"source":"UniProtKB","id":"O88890","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | Motif: {"description":"ITSM 1","evidences":[{"source":"PubMed","id":"11823424","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine; by FYN","evidences":[{"source":"PubMed","id":"11689425","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11806999","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
