1K9Z
The PAPase Hal2p complexed with zinc ions
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000103 | biological_process | sulfate assimilation |
| A | 0005575 | cellular_component | cellular_component |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006790 | biological_process | sulfur compound metabolic process |
| A | 0008441 | molecular_function | 3'(2'),5'-bisphosphate nucleotidase activity |
| A | 0016078 | biological_process | tRNA decay |
| A | 0042538 | biological_process | hyperosmotic salinity response |
| A | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
| A | 0071265 | biological_process | L-methionine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | GLU72 |
| A | ZN402 |
| A | HOH502 |
| A | HOH503 |
| A | HOH517 |
| A | HOH518 |
| A | HOH793 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 402 |
| Chain | Residue |
| A | ILE144 |
| A | ZN401 |
| A | HOH518 |
| A | HOH794 |
| A | GLU72 |
| A | ASP142 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 403 |
| Chain | Residue |
| A | ASP142 |
| A | ASP145 |
| A | ASP294 |
| A | HOH505 |
| A | HOH511 |
| A | HOH803 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 404 |
| Chain | Residue |
| A | GLU27 |
| A | GLU89 |
| A | HOH566 |
| A | HOH653 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 405 |
| Chain | Residue |
| A | HIS221 |
| A | HIS224 |
| A | HOH560 |
| A | HOH665 |
| A | HOH668 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 406 |
| Chain | Residue |
| A | GLU235 |
| A | HIS244 |
| A | HIS261 |
| A | HOH613 |
| A | HOH720 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 407 |
| Chain | Residue |
| A | HIS191 |
| A | GLU192 |
| A | ZN408 |
| A | HOH620 |
| A | HOH646 |
| A | HOH729 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 408 |
| Chain | Residue |
| A | GLU131 |
| A | HIS191 |
| A | ZN407 |
| A | HOH522 |
| A | HOH620 |
| A | HOH646 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 409 |
| Chain | Residue |
| A | ASP315 |
| A | ASP342 |
| A | HOH748 |
| A | HOH786 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BME A 501 |
| Chain | Residue |
| A | MET313 |
| A | CYS349 |
| A | GLN353 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"12126627","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10656801","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12126627","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1K9Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QGX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12126627","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1K9Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KA1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12126627","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KA1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10656801","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12126627","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"OCT-2001","submissionDatabase":"PDB data bank","title":"Hal2p: Ion selectivity and implications on inhibition mechanism.","authors":["Patel S.","Albert A.","Blundell T.L."]}},{"source":"PDB","id":"1K9Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KA0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QGX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ima |
| Chain | Residue | Details |
| A | THR147 | |
| A | GLU72 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ima |
| Chain | Residue | Details |
| A | LYS32 | |
| A | THR147 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ima |
| Chain | Residue | Details |
| A | ASP294 | |
| A | ASP49 | |
| A | THR147 |
| site_id | MCSA1 |
| Number of Residues | 7 |
| Details | M-CSA 904 |
| Chain | Residue | Details |
| A | ASP49 | proton acceptor, proton donor |
| A | GLU72 | metal ligand |
| A | ASP142 | metal ligand |
| A | ILE144 | metal ligand |
| A | ASP145 | metal ligand |
| A | THR147 | proton acceptor, proton donor, proton relay |
| A | ASP294 | metal ligand |
