1K3Z
X-ray crystal structure of the IkBb/NF-kB p65 homodimer complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q15653 |
| Chain | Residue | Details |
| D | GLU313 | |
| D | GLU318 | |
| B | LYS218 | |
| B | LYS221 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q04206 |
| Chain | Residue | Details |
| A | THR254 | |
| B | THR254 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by RPS6KA4 and RPS6KA5 => ECO:0000250|UniProtKB:Q04206 |
| Chain | Residue | Details |
| A | SER276 | |
| B | SER276 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q04206 |
| Chain | Residue | Details |
| A | SER281 | |
| B | SER281 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; by SETD6; alternate => ECO:0000269|PubMed:21131967 |
| Chain | Residue | Details |
| A | LYS310 | |
| B | LYS310 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by PKC/PRKCZ => ECO:0000269|PubMed:12881425, ECO:0000269|PubMed:21131967 |
| Chain | Residue | Details |
| A | SER311 | |
| B | SER311 |
