Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1K3F

Uridine Phosphorylase from E. coli, Refined in the Monoclinic Crystal Lattice

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004850	molecular_function	uridine phosphorylase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006218	biological_process	uridine catabolic process
A	0006974	biological_process	DNA damage response
A	0009116	biological_process	nucleoside metabolic process
A	0009164	biological_process	nucleoside catabolic process
A	0009166	biological_process	nucleotide catabolic process
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0016763	molecular_function	pentosyltransferase activity
A	0030955	molecular_function	potassium ion binding
A	0032991	cellular_component	protein-containing complex
A	0042802	molecular_function	identical protein binding
A	0044206	biological_process	UMP salvage
A	0046050	biological_process	UMP catabolic process
B	0003824	molecular_function	catalytic activity
B	0004850	molecular_function	uridine phosphorylase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006218	biological_process	uridine catabolic process
B	0006974	biological_process	DNA damage response
B	0009116	biological_process	nucleoside metabolic process
B	0009164	biological_process	nucleoside catabolic process
B	0009166	biological_process	nucleotide catabolic process
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0016763	molecular_function	pentosyltransferase activity
B	0030955	molecular_function	potassium ion binding
B	0032991	cellular_component	protein-containing complex
B	0042802	molecular_function	identical protein binding
B	0044206	biological_process	UMP salvage
B	0046050	biological_process	UMP catabolic process
C	0003824	molecular_function	catalytic activity
C	0004850	molecular_function	uridine phosphorylase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006218	biological_process	uridine catabolic process
C	0006974	biological_process	DNA damage response
C	0009116	biological_process	nucleoside metabolic process
C	0009164	biological_process	nucleoside catabolic process
C	0009166	biological_process	nucleotide catabolic process
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0016763	molecular_function	pentosyltransferase activity
C	0030955	molecular_function	potassium ion binding
C	0032991	cellular_component	protein-containing complex
C	0042802	molecular_function	identical protein binding
C	0044206	biological_process	UMP salvage
C	0046050	biological_process	UMP catabolic process
D	0003824	molecular_function	catalytic activity
D	0004850	molecular_function	uridine phosphorylase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006218	biological_process	uridine catabolic process
D	0006974	biological_process	DNA damage response
D	0009116	biological_process	nucleoside metabolic process
D	0009164	biological_process	nucleoside catabolic process
D	0009166	biological_process	nucleotide catabolic process
D	0016740	molecular_function	transferase activity
D	0016757	molecular_function	glycosyltransferase activity
D	0016763	molecular_function	pentosyltransferase activity
D	0030955	molecular_function	potassium ion binding
D	0032991	cellular_component	protein-containing complex
D	0042802	molecular_function	identical protein binding
D	0044206	biological_process	UMP salvage
D	0046050	biological_process	UMP catabolic process
E	0003824	molecular_function	catalytic activity
E	0004850	molecular_function	uridine phosphorylase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006218	biological_process	uridine catabolic process
E	0006974	biological_process	DNA damage response
E	0009116	biological_process	nucleoside metabolic process
E	0009164	biological_process	nucleoside catabolic process
E	0009166	biological_process	nucleotide catabolic process
E	0016740	molecular_function	transferase activity
E	0016757	molecular_function	glycosyltransferase activity
E	0016763	molecular_function	pentosyltransferase activity
E	0030955	molecular_function	potassium ion binding
E	0032991	cellular_component	protein-containing complex
E	0042802	molecular_function	identical protein binding
E	0044206	biological_process	UMP salvage
E	0046050	biological_process	UMP catabolic process
F	0003824	molecular_function	catalytic activity
F	0004850	molecular_function	uridine phosphorylase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006218	biological_process	uridine catabolic process
F	0006974	biological_process	DNA damage response
F	0009116	biological_process	nucleoside metabolic process
F	0009164	biological_process	nucleoside catabolic process
F	0009166	biological_process	nucleotide catabolic process
F	0016740	molecular_function	transferase activity
F	0016757	molecular_function	glycosyltransferase activity
F	0016763	molecular_function	pentosyltransferase activity
F	0030955	molecular_function	potassium ion binding
F	0032991	cellular_component	protein-containing complex
F	0042802	molecular_function	identical protein binding
F	0044206	biological_process	UMP salvage
F	0046050	biological_process	UMP catabolic process

Functional Information from PROSITE/UniProt

site_id	PS01232
Number of Residues	16
Details	PNP_UDP_1 Purine and other phosphorylases family 1 signature. StGIGgPStSIaveEL

Chain	Residue	Details
A	SER66-LEU81

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
A	GLU80
A	HIS8
A	ARG223

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
B	ARG1223
B	GLU1080
B	HIS1008

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
C	ARG2223
C	GLU2080
C	HIS2008

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
D	GLU3080
D	HIS3008
D	ARG3223

site_id	CSA5
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
E	HIS4008
E	GLU4080
E	ARG4223

site_id	CSA6
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
F	GLU5080
F	ARG5223
F	HIS5008

site_id	MCSA1
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
A	HIS8	proton acceptor, proton donor
A	GLU80	electrostatic stabiliser, polar interaction
A	ARG168	proton acceptor, proton donor
A	ARG223	electrostatic stabiliser, polar interaction

site_id	MCSA2
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
B	HIS1008	proton acceptor, proton donor
B	GLU1080	electrostatic stabiliser, polar interaction
B	ARG1168	proton acceptor, proton donor
B	ARG1223	electrostatic stabiliser, polar interaction

site_id	MCSA3
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
C	HIS2008	proton acceptor, proton donor
C	GLU2080	electrostatic stabiliser, polar interaction
C	ARG2168	proton acceptor, proton donor
C	ARG2223	electrostatic stabiliser, polar interaction

site_id	MCSA4
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
D	HIS3008	proton acceptor, proton donor
D	GLU3080	electrostatic stabiliser, polar interaction
D	ARG3168	proton acceptor, proton donor
D	ARG3223	electrostatic stabiliser, polar interaction

site_id	MCSA5
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
E	HIS4008	proton acceptor, proton donor
E	GLU4080	electrostatic stabiliser, polar interaction
E	ARG4168	proton acceptor, proton donor
E	ARG4223	electrostatic stabiliser, polar interaction

site_id	MCSA6
Number of Residues	4
Details	M-CSA 787

Chain	Residue	Details
F	HIS5008	proton acceptor, proton donor
F	GLU5080	electrostatic stabiliser, polar interaction
F	ARG5168	proton acceptor, proton donor
F	ARG5223	electrostatic stabiliser, polar interaction

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)