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1K2W

Crystal structure of sorbitol dehydrogenase from R. sphaeroides

Functional Information from GO Data
ChainGOidnamespacecontents
A0003939molecular_functionL-iditol 2-dehydrogenase (NAD+) activity
A0016491molecular_functionoxidoreductase activity
A0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A0047713molecular_functiongalactitol 2-dehydrogenase activity
B0003939molecular_functionL-iditol 2-dehydrogenase (NAD+) activity
B0016491molecular_functionoxidoreductase activity
B0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B0047713molecular_functiongalactitol 2-dehydrogenase activity
Functional Information from PROSITE/UniProt
site_idPS00061
Number of Residues29
DetailsADH_SHORT Short-chain dehydrogenases/reductases family signature. SqagrrgealVgvYCATKAAViSLTqSAG
ChainResidueDetails
ASER139-GLY167

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10001
ChainResidueDetails
ATYR152
BTYR152

site_idSWS_FT_FI2
Number of Residues14
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q9ZNN8
ChainResidueDetails
AARG15
BASP59
BASN86
BTYR152
BLYS156
BPRO182
AASP36
AASP59
AASN86
ATYR152
ALYS156
APRO182
BARG15
BASP36

Catalytic Information from CSA
site_idCSA1
Number of Residues3
DetailsAnnotated By Reference To The Literature 1eq2
ChainResidueDetails
ATYR152
ALYS156
ASER139

site_idCSA2
Number of Residues3
DetailsAnnotated By Reference To The Literature 1eq2
ChainResidueDetails
BTYR152
BLYS156
BSER139

site_idCSA3
Number of Residues4
DetailsAnnotated By Reference To The Literature 1eq2
ChainResidueDetails
ATYR152
ALYS156
ASER139
AASN110

site_idCSA4
Number of Residues4
DetailsAnnotated By Reference To The Literature 1eq2
ChainResidueDetails
BTYR152
BLYS156
BSER139
BASN110

site_idCSA5
Number of Residues2
DetailsAnnotated By Reference To The Literature 1eq2
ChainResidueDetails
ALYS156
AVAL149

site_idCSA6
Number of Residues2
DetailsAnnotated By Reference To The Literature 1eq2
ChainResidueDetails
BLYS156
BVAL149

site_idCSA7
Number of Residues2
DetailsAnnotated By Reference To The Literature 1eq2
ChainResidueDetails
ATYR152
ALYS156

site_idCSA8
Number of Residues2
DetailsAnnotated By Reference To The Literature 1eq2
ChainResidueDetails
BTYR152
BLYS156

225946

PDB entries from 2024-10-09

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