1JZW
Arsenate Reductase + Sodium Arsenate From E. coli
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | CSR12 |
| A | HOH719 |
| A | GLY13 |
| A | THR14 |
| A | ASN62 |
| A | GLU67 |
| A | SO3401 |
| A | HOH534 |
| A | HOH587 |
| A | HOH632 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | ARG107 |
| A | HOH599 |
| A | HOH604 |
| A | HOH684 |
| A | HOH699 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 303 |
| Chain | Residue |
| A | THR14 |
| A | ASN17 |
| A | PRO108 |
| A | SER109 |
| A | LYS126 |
| A | HOH534 |
| A | HOH593 |
| A | HOH679 |
| A | HOH700 |
| A | HOH727 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO3 A 401 |
| Chain | Residue |
| A | CSR12 |
| A | ARG60 |
| A | ARG94 |
| A | SO4301 |
| A | HOH604 |
| A | HOH737 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CS A 501 |
| Chain | Residue |
| A | LEU113 |
| A | LEU113 |
| A | ASP114 |
| A | ASP114 |
| A | LEU116 |
| A | LEU116 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CS A 502 |
| Chain | Residue |
| A | GLU67 |
| A | HOH719 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CS A 503 |
| Chain | Residue |
| A | PRO38 |
| A | GLU43 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CS A 504 |
| Chain | Residue |
| A | GLY26 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CS A 505 |
| Chain | Residue |
| A | GLU64 |
| A | GLN87 |
| A | HOH614 |
| A | HOH697 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile; cysteine thioarsenate intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU01282","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11709171","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15295115","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7577935","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for activity. Lowers pKa of the active site Cys","evidences":[{"source":"PubMed","id":"8969183","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Site: {"description":"Important for activity. Involved in arsenate binding and transition-state stabilization","evidences":[{"source":"PubMed","id":"11709171","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14592722","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15295115","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
