1JYE

Structure of a Dimeric Lac Repressor with C-terminal Deletion and K84L Substitution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
A	0001217	molecular_function	DNA-binding transcription repressor activity
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005829	cellular_component	cytosol
A	0006355	biological_process	regulation of DNA-templated transcription
A	0042802	molecular_function	identical protein binding
A	0045892	biological_process	negative regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 350

Chain	Residue
A	ARG197
A	ASN246
A	ASP274
A	GLN291
A	HOH354
A	HOH576

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Functional Information from PROSITE/UniProt

site_id	PS00356
Number of Residues	19
Details	HTH_LACI_1 LacI-type HTH domain signature. LyDVAeyAgVSyqTVsrVV

Chain	Residue	Details
A	LEU6-VAL24

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	19
Details	DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00111

Chain	Residue	Details
A	LEU6-ASN25

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