1JX2

CRYSTAL STRUCTURE OF THE NUCLEOTIDE-FREE DYNAMIN A GTPASE DOMAIN, DETERMINED AS MYOSIN FUSION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003774	molecular_function	cytoskeletal motor activity
A	0003924	molecular_function	GTPase activity
A	0005524	molecular_function	ATP binding
A	0005525	molecular_function	GTP binding
A	0016459	cellular_component	myosin complex
A	0051015	molecular_function	actin filament binding

Functional Information from PROSITE/UniProt

site_id	PS00410
Number of Residues	10
Details	G_DYNAMIN_1 Dynamin-type guanine nucleotide-binding (G) domain signature. LPRGSGIVTR

Chain	Residue	Details
A	LEU835-ARG844

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING:

Chain	Residue	Details
A	GLY190

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6,N6-dimethyllysine => ECO:0000255

Chain	Residue	Details
A	LYS141

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site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250|UniProtKB:O00429

Chain	Residue	Details
A	GLY816
A	THR991
A	ASN1022

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	8
Details	M-CSA 534

Chain	Residue	Details
A	SER192	proton acceptor, proton donor, proton relay
A	GLY193	electrostatic stabiliser
A	THR197	metal ligand
A	ASN244	electrostatic stabiliser
A	SER247	proton acceptor, proton donor, proton relay
A	SER248	metal ligand
A	GLY468	electrostatic stabiliser
A	GLU470	electrostatic stabiliser, proton acceptor, proton donor

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