1JV4

Crystal structure of recombinant major mouse urinary protein (rmup) at 1.75 A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003674	molecular_function	molecular_function
A	0005009	molecular_function	insulin receptor activity
A	0005550	molecular_function	pheromone binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005634	cellular_component	nucleus
A	0005829	cellular_component	cytosol
A	0006112	biological_process	energy reserve metabolic process
A	0007005	biological_process	mitochondrion organization
A	0008150	biological_process	biological_process
A	0008286	biological_process	insulin receptor signaling pathway
A	0009060	biological_process	aerobic respiration
A	0010628	biological_process	positive regulation of gene expression
A	0010888	biological_process	negative regulation of lipid storage
A	0010907	biological_process	positive regulation of glucose metabolic process
A	0031649	biological_process	heat generation
A	0036094	molecular_function	small molecule binding
A	0042593	biological_process	glucose homeostasis
A	0045475	biological_process	locomotor rhythm
A	0045721	biological_process	negative regulation of gluconeogenesis
A	0045834	biological_process	positive regulation of lipid metabolic process
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0051055	biological_process	negative regulation of lipid biosynthetic process
A	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A	0061179	biological_process	negative regulation of insulin secretion involved in cellular response to glucose stimulus
A	0071396	biological_process	cellular response to lipid

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD A 163

Chain	Residue
A	GLU18
A	HIS20
A	GLU75
A	HOH186
A	HOH199
A	HOH304

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD A 164

Chain	Residue
A	HOH203
A	HOH219
A	HIS104
A	GLN115
A	HIS141

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD A 165

Chain	Residue
A	HIS46
A	HOH234

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD A 166

Chain	Residue
A	GLU18
A	GLU75

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site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD A 167

Chain	Residue
A	GLU63
A	HOH274

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site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD A 168

Chain	Residue
A	GLU43
A	HOH230

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site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD A 169

Chain	Residue
A	ASP72
A	HOH295
A	HOH318

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site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE TZL A 170

Chain	Residue
A	PHE90
A	TYR120

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Functional Information from PROSITE/UniProt

site_id	PS00213
Number of Residues	14
Details	LIPOCALIN Lipocalin signature. NFNveKINGEWHTI

Chain	Residue	Details
A	ASN9-ILE22

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