1JR3
Crystal Structure of the Processivity Clamp Loader Gamma Complex of E. coli DNA Polymerase III
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006260 | biological_process | DNA replication |
| A | 0009360 | cellular_component | DNA polymerase III complex |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006260 | biological_process | DNA replication |
| B | 0009360 | cellular_component | DNA polymerase III complex |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006260 | biological_process | DNA replication |
| C | 0009360 | cellular_component | DNA polymerase III complex |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003689 | molecular_function | DNA clamp loader activity |
| D | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0006260 | biological_process | DNA replication |
| D | 0006261 | biological_process | DNA-templated DNA replication |
| D | 0009360 | cellular_component | DNA polymerase III complex |
| D | 0030894 | cellular_component | replisome |
| D | 0034061 | molecular_function | DNA polymerase activity |
| D | 0043846 | cellular_component | DNA polymerase III, clamp loader complex |
| D | 0071897 | biological_process | DNA biosynthetic process |
| E | 0003677 | molecular_function | DNA binding |
| E | 0003689 | molecular_function | DNA clamp loader activity |
| E | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0006260 | biological_process | DNA replication |
| E | 0006261 | biological_process | DNA-templated DNA replication |
| E | 0008408 | molecular_function | 3'-5' exonuclease activity |
| E | 0009360 | cellular_component | DNA polymerase III complex |
| E | 0030894 | cellular_component | replisome |
| E | 0034061 | molecular_function | DNA polymerase activity |
| E | 0043846 | cellular_component | DNA polymerase III, clamp loader complex |
| E | 0071897 | biological_process | DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 400 |
| Chain | Residue |
| A | CYS64 |
| A | CYS73 |
| A | CYS76 |
| A | CYS79 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1500 |
| Chain | Residue |
| A | LYS51 |
| A | THR52 |
| A | ARG215 |
| A | THR46 |
| A | ARG47 |
| A | GLY48 |
| A | VAL49 |
| A | GLY50 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 400 |
| Chain | Residue |
| B | CYS73 |
| B | CYS76 |
| B | CYS79 |
| B | CYS2064 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2500 |
| Chain | Residue |
| B | ARG215 |
| B | THR2046 |
| B | GLY2048 |
| B | VAL2049 |
| B | GLY2050 |
| B | LYS2051 |
| B | THR2052 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 400 |
| Chain | Residue |
| C | CYS64 |
| C | CYS73 |
| C | CYS76 |
| C | CYS79 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 5500 |
| Chain | Residue |
| C | GLY48 |
| C | VAL49 |
| C | GLY50 |
| C | LYS51 |
| C | THR52 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN E 400 |
| Chain | Residue |
| E | CYS50 |
| E | CYS59 |
| E | CYS62 |
| E | CYS65 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY45 | |
| B | GLY2045 | |
| C | GLY45 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11525729, ECO:0007744|PDB:1JR3 |
| Chain | Residue | Details |
| A | CYS64 | |
| C | CYS73 | |
| C | CYS76 | |
| C | CYS79 | |
| A | CYS73 | |
| A | CYS76 | |
| A | CYS79 | |
| B | CYS2064 | |
| B | CYS73 | |
| B | CYS76 | |
| B | CYS79 | |
| C | CYS64 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1g8p |
| Chain | Residue | Details |
| A | VAL253 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1g8p |
| Chain | Residue | Details |
| B | VAL253 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1g8p |
| Chain | Residue | Details |
| C | VAL253 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1g8p |
| Chain | Residue | Details |
| A | ARG215 | |
| A | LYS51 | |
| A | LYS141 |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1g8p |
| Chain | Residue | Details |
| B | ARG215 | |
| B | LYS2051 | |
| B | LYS141 |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1g8p |
| Chain | Residue | Details |
| C | ARG215 | |
| C | LYS51 | |
| C | LYS141 |
| site_id | CSA7 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1g8p |
| Chain | Residue | Details |
| A | ARG215 | |
| A | THR157 |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1g8p |
| Chain | Residue | Details |
| B | ARG215 | |
| B | THR157 |
| site_id | CSA9 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1g8p |
| Chain | Residue | Details |
| C | ARG215 | |
| C | THR157 |
