1JR2

Structure of Uroporphyrinogen III Synthase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004852	molecular_function	uroporphyrinogen-III synthase activity
A	0005542	molecular_function	folic acid binding
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0006779	biological_process	porphyrin-containing compound biosynthetic process
A	0006780	biological_process	uroporphyrinogen III biosynthetic process
A	0006782	biological_process	protoporphyrinogen IX biosynthetic process
A	0006783	biological_process	heme biosynthetic process
A	0006784	biological_process	heme A biosynthetic process
A	0006785	biological_process	heme B biosynthetic process
A	0016829	molecular_function	lyase activity
A	0033014	biological_process	tetrapyrrole biosynthetic process
A	0048034	biological_process	heme O biosynthetic process
A	0070541	biological_process	response to platinum ion
A	0071243	biological_process	cellular response to arsenic-containing substance
A	0071418	biological_process	cellular response to amine stimulus
B	0004852	molecular_function	uroporphyrinogen-III synthase activity
B	0005542	molecular_function	folic acid binding
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0006779	biological_process	porphyrin-containing compound biosynthetic process
B	0006780	biological_process	uroporphyrinogen III biosynthetic process
B	0006782	biological_process	protoporphyrinogen IX biosynthetic process
B	0006783	biological_process	heme biosynthetic process
B	0006784	biological_process	heme A biosynthetic process
B	0006785	biological_process	heme B biosynthetic process
B	0016829	molecular_function	lyase activity
B	0033014	biological_process	tetrapyrrole biosynthetic process
B	0048034	biological_process	heme O biosynthetic process
B	0070541	biological_process	response to platinum ion
B	0071243	biological_process	cellular response to arsenic-containing substance
B	0071418	biological_process	cellular response to amine stimulus

Functional Information from PROSITE/UniProt

site_id	PS00070
Number of Residues	12
Details	ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. LdTEGETCGNAE

Chain	Residue	Details
A	LEU112-GLU123

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