1JPM
L-Ala-D/L-Glu Epimerase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0006518 | biological_process | peptide metabolic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016854 | molecular_function | racemase and epimerase activity |
| A | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071555 | biological_process | cell wall organization |
| A | 0103031 | molecular_function | L-Ala-D/L-Glu epimerase activity |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0006518 | biological_process | peptide metabolic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016854 | molecular_function | racemase and epimerase activity |
| B | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| B | 0016998 | biological_process | cell wall macromolecule catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0071555 | biological_process | cell wall organization |
| B | 0103031 | molecular_function | L-Ala-D/L-Glu epimerase activity |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0006518 | biological_process | peptide metabolic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0016854 | molecular_function | racemase and epimerase activity |
| C | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| C | 0016998 | biological_process | cell wall macromolecule catabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0071555 | biological_process | cell wall organization |
| C | 0103031 | molecular_function | L-Ala-D/L-Glu epimerase activity |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0006518 | biological_process | peptide metabolic process |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0016854 | molecular_function | racemase and epimerase activity |
| D | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| D | 0016998 | biological_process | cell wall macromolecule catabolic process |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0071555 | biological_process | cell wall organization |
| D | 0103031 | molecular_function | L-Ala-D/L-Glu epimerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 1001 |
| Chain | Residue |
| D | ASP191 |
| D | GLU219 |
| D | ASP244 |
| D | HOH1032 |
| D | HOH1056 |
| D | HOH1091 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 1002 |
| Chain | Residue |
| B | HOH1125 |
| B | HOH1126 |
| B | HOH1127 |
| B | ASP191 |
| B | GLU219 |
| B | ASP244 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1003 |
| Chain | Residue |
| A | ASP191 |
| A | GLU219 |
| A | ASP244 |
| A | HOH2039 |
| A | HOH2040 |
| A | HOH2041 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 1004 |
| Chain | Residue |
| C | ASP191 |
| C | GLU219 |
| C | ASP244 |
| C | HOH1058 |
| C | HOH1059 |
| C | HOH1094 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 2001 |
| Chain | Residue |
| A | ALA42 |
| A | VAL43 |
| A | TRP45 |
| A | GLN113 |
| A | ILE354 |
| C | SER40 |
| C | GLY41 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor; specific for (R)-substrate epimerization","evidences":[{"source":"PubMed","id":"15301535","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor; specific for (S)-substrate epimerization","evidences":[{"source":"PubMed","id":"15301535","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15301535","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11747448","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15301535","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| A | ASP321 | |
| A | LYS160 | |
| A | LYS162 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| B | ASP321 | |
| B | LYS160 | |
| B | LYS162 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| C | ASP321 | |
| C | LYS160 | |
| C | LYS162 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| D | ASP321 | |
| D | LYS160 | |
| D | LYS162 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| A | LYS268 | |
| A | LYS162 |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| B | LYS268 | |
| B | LYS162 |
| site_id | CSA7 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| C | LYS268 | |
| C | LYS162 |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| D | LYS268 | |
| D | LYS162 |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 957 |
| Chain | Residue | Details |
| A | LYS162 | proton acceptor, proton donor |
| A | ASP191 | metal ligand |
| A | GLU219 | metal ligand |
| A | ASP244 | metal ligand |
| A | LYS268 | proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 957 |
| Chain | Residue | Details |
| B | LYS162 | proton acceptor, proton donor |
| B | ASP191 | metal ligand |
| B | GLU219 | metal ligand |
| B | ASP244 | metal ligand |
| B | LYS268 | proton acceptor, proton donor |
| site_id | MCSA3 |
| Number of Residues | 5 |
| Details | M-CSA 957 |
| Chain | Residue | Details |
| C | LYS162 | proton acceptor, proton donor |
| C | ASP191 | metal ligand |
| C | GLU219 | metal ligand |
| C | ASP244 | metal ligand |
| C | LYS268 | proton acceptor, proton donor |
| site_id | MCSA4 |
| Number of Residues | 5 |
| Details | M-CSA 957 |
| Chain | Residue | Details |
| D | LYS162 | proton acceptor, proton donor |
| D | ASP191 | metal ligand |
| D | GLU219 | metal ligand |
| D | ASP244 | metal ligand |
| D | LYS268 | proton acceptor, proton donor |
