Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1JKU

Crystal Structure of Manganese Catalase from Lactobacillus plantarum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004096	molecular_function	catalase activity
A	0004601	molecular_function	peroxidase activity
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
A	0098869	biological_process	cellular oxidant detoxification
B	0004096	molecular_function	catalase activity
B	0004601	molecular_function	peroxidase activity
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0098869	biological_process	cellular oxidant detoxification
C	0004096	molecular_function	catalase activity
C	0004601	molecular_function	peroxidase activity
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
C	0098869	biological_process	cellular oxidant detoxification
D	0004096	molecular_function	catalase activity
D	0004601	molecular_function	peroxidase activity
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding
D	0098869	biological_process	cellular oxidant detoxification
E	0004096	molecular_function	catalase activity
E	0004601	molecular_function	peroxidase activity
E	0016491	molecular_function	oxidoreductase activity
E	0046872	molecular_function	metal ion binding
E	0098869	biological_process	cellular oxidant detoxification
F	0004096	molecular_function	catalase activity
F	0004601	molecular_function	peroxidase activity
F	0016491	molecular_function	oxidoreductase activity
F	0046872	molecular_function	metal ion binding
F	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 1272

Chain	Residue
A	ASP57
A	ASP61
F	ASN218
F	SER220
F	GLY222

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 2272

Chain	Residue
C	GLY222
C	HOH3332
B	ASP57
B	ASP61
C	ASN218
C	SER220

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 3272

Chain	Residue
B	ASN218
B	SER220
B	GLY222
C	ASP57
C	ASP61

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D 4272

Chain	Residue
D	ASP57
D	ASP61
E	ASN218
E	SER220
E	GLY222

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA E 5272

Chain	Residue
D	ASN218
D	SER220
D	GLY222
D	SER225
D	HOH4334
E	ASP57
E	ASP61

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA F 6272

Chain	Residue
A	ASN218
A	SER220
A	GLY222
A	SER225
F	ASP57
F	ASP61

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OH A 1269

Chain	Residue
A	GLU66
A	HIS69
A	HIS181
A	MN31267
A	MN31268
A	OH1270
A	OH1271

site_id	AC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE OH A 1270

Chain	Residue
A	GLU35
A	GLU66
A	ARG147
A	GLU148
A	GLU178
A	MN31267
A	MN31268
A	OH1269
A	OH1271

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OH A 1271

Chain	Residue
A	GLU35
A	HIS69
A	LEU174
A	GLU178
A	MN31267
A	OH1269
A	OH1270

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OH B 2269

Chain	Residue
B	GLU66
B	HIS69
B	HIS181
B	MN32267
B	MN32268
B	OH2270
B	OH2271

site_id	BC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE OH B 2270

Chain	Residue
B	GLU35
B	GLU66
B	ARG147
B	GLU148
B	GLU178
B	MN32267
B	MN32268
B	OH2269
B	OH2271

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OH B 2271

Chain	Residue
B	GLU35
B	HIS69
B	LEU174
B	GLU178
B	MN32267
B	OH2269
B	OH2270

site_id	BC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE OH C 3269

Chain	Residue
C	GLU35
C	GLU66
C	HIS69
C	HIS181
C	MN33267
C	MN33268
C	OH3270
C	OH3271

site_id	BC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE OH C 3270

Chain	Residue
C	GLU35
C	GLU66
C	ARG147
C	GLU148
C	GLU178
C	MN33267
C	MN33268
C	OH3269
C	OH3271

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OH C 3271

Chain	Residue
C	LEU174
C	GLU178
C	MN33267
C	OH3269
C	OH3270
C	GLU35
C	HIS69

site_id	BC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE OH D 4269

Chain	Residue
D	GLU66
D	HIS69
D	GLU148
D	HIS181
D	MN34267
D	MN34268
D	OH4270
D	OH4271

site_id	BC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE OH D 4270

Chain	Residue
D	GLU35
D	GLU66
D	ARG147
D	GLU148
D	GLU178
D	MN34267
D	MN34268
D	OH4269
D	OH4271

site_id	BC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OH D 4271

Chain	Residue
D	GLU35
D	HIS69
D	LEU174
D	GLU178
D	MN34267
D	OH4269
D	OH4270

site_id	CC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OH E 5269

Chain	Residue
E	GLU66
E	HIS69
E	HIS181
E	MN35267
E	MN35268
E	OH5270
E	OH5271

site_id	CC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE OH E 5270

Chain	Residue
E	GLU35
E	GLU66
E	ARG147
E	GLU148
E	GLU178
E	MN35267
E	MN35268
E	OH5269
E	OH5271

site_id	CC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OH E 5271

Chain	Residue
E	GLU35
E	HIS69
E	LEU174
E	GLU178
E	MN35267
E	OH5269
E	OH5270

site_id	CC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OH F 6269

Chain	Residue
F	GLU66
F	HIS69
F	HIS181
F	MN36267
F	MN36268
F	OH6270
F	OH6271

site_id	CC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE OH F 6270

Chain	Residue
F	GLU35
F	GLU66
F	ARG147
F	GLU148
F	GLU178
F	MN36267
F	MN36268
F	OH6269
F	OH6271

site_id	CC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OH F 6271

Chain	Residue
F	GLU35
F	HIS69
F	LEU174
F	GLU178
F	MN36267
F	OH6269
F	OH6270

site_id	CC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 A 1267

Chain	Residue
A	GLU35
A	GLU66
A	HIS69
A	MN31268
A	OH1269
A	OH1270
A	OH1271

site_id	CC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 A 1268

Chain	Residue
A	GLU66
A	ARG147
A	GLU148
A	HIS181
A	MN31267
A	OH1269
A	OH1270

site_id	CC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 B 2267

Chain	Residue
B	GLU35
B	GLU66
B	HIS69
B	MN32268
B	OH2269
B	OH2270
B	OH2271

site_id	DC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 B 2268

Chain	Residue
B	GLU66
B	ARG147
B	GLU148
B	HIS181
B	MN32267
B	OH2269
B	OH2270

site_id	DC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 C 3267

Chain	Residue
C	GLU35
C	GLU66
C	HIS69
C	MN33268
C	OH3269
C	OH3270
C	OH3271

site_id	DC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 C 3268

Chain	Residue
C	GLU66
C	ARG147
C	GLU148
C	HIS181
C	MN33267
C	OH3269
C	OH3270

site_id	DC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 D 4267

Chain	Residue
D	GLU35
D	GLU66
D	HIS69
D	MN34268
D	OH4269
D	OH4270
D	OH4271

site_id	DC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 D 4268

Chain	Residue
D	GLU66
D	ARG147
D	GLU148
D	HIS181
D	MN34267
D	OH4269
D	OH4270

site_id	DC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 E 5267

Chain	Residue
E	GLU35
E	GLU66
E	HIS69
E	MN35268
E	OH5269
E	OH5270
E	OH5271

site_id	DC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 E 5268

Chain	Residue
E	GLU66
E	ARG147
E	GLU148
E	HIS181
E	MN35267
E	OH5269
E	OH5270

site_id	DC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 F 6267

Chain	Residue
F	GLU35
F	GLU66
F	HIS69
F	MN36268
F	OH6269
F	OH6270
F	OH6271

site_id	DC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 F 6268

Chain	Residue
F	GLU66
F	ARG147
F	GLU148
F	HIS181
F	MN36267
F	OH6269
F	OH6270

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	138
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	66
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11587647","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12631270","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1JKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JKV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1O9I","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1o9i

Chain	Residue	Details
A	GLU178

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1o9i

Chain	Residue	Details
B	GLU178

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1o9i

Chain	Residue	Details
C	GLU178

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1o9i

Chain	Residue	Details
D	GLU178

site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1o9i

Chain	Residue	Details
E	GLU178

site_id	CSA6
Number of Residues	1
Details	Annotated By Reference To The Literature 1o9i

Chain	Residue	Details
F	GLU178

site_id	MCSA1
Number of Residues	6
Details	M-CSA 572

Chain	Residue	Details
A	GLU35	metal ligand
A	GLU66	metal ligand
A	HIS69	metal ligand
A	GLU148	metal ligand
A	GLU178	proton acceptor, proton donor, proton shuttle (general acid/base)
A	HIS181	metal ligand

site_id	MCSA2
Number of Residues	6
Details	M-CSA 572

Chain	Residue	Details
B	GLU35	metal ligand
B	GLU66	metal ligand
B	HIS69	metal ligand
B	GLU148	metal ligand
B	GLU178	proton acceptor, proton donor, proton shuttle (general acid/base)
B	HIS181	metal ligand

site_id	MCSA3
Number of Residues	6
Details	M-CSA 572

Chain	Residue	Details
C	GLU35	metal ligand
C	GLU66	metal ligand
C	HIS69	metal ligand
C	GLU148	metal ligand
C	GLU178	proton acceptor, proton donor, proton shuttle (general acid/base)
C	HIS181	metal ligand

site_id	MCSA4
Number of Residues	6
Details	M-CSA 572

Chain	Residue	Details
D	GLU35	metal ligand
D	GLU66	metal ligand
D	HIS69	metal ligand
D	GLU148	metal ligand
D	GLU178	proton acceptor, proton donor, proton shuttle (general acid/base)
D	HIS181	metal ligand

site_id	MCSA5
Number of Residues	6
Details	M-CSA 572

Chain	Residue	Details
E	GLU35	metal ligand
E	GLU66	metal ligand
E	HIS69	metal ligand
E	GLU148	metal ligand
E	GLU178	proton acceptor, proton donor, proton shuttle (general acid/base)
E	HIS181	metal ligand

site_id	MCSA6
Number of Residues	6
Details	M-CSA 572

Chain	Residue	Details
F	GLU35	metal ligand
F	GLU66	metal ligand
F	HIS69	metal ligand
F	GLU148	metal ligand
F	GLU178	proton acceptor, proton donor, proton shuttle (general acid/base)
F	HIS181	metal ligand

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)