1JG5

CRYSTAL STRUCTURE OF RAT GTP CYCLOHYDROLASE I FEEDBACK REGULATORY PROTEIN, GFRP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004857	molecular_function	enzyme inhibitor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0009890	biological_process	negative regulation of biosynthetic process
A	0016020	cellular_component	membrane
A	0016597	molecular_function	amino acid binding
A	0019899	molecular_function	enzyme binding
A	0030425	cellular_component	dendrite
A	0030742	molecular_function	GTP-dependent protein binding
A	0031965	cellular_component	nuclear membrane
A	0032991	cellular_component	protein-containing complex
A	0042470	cellular_component	melanosome
A	0042802	molecular_function	identical protein binding
A	0044549	molecular_function	GTP cyclohydrolase binding
A	0044877	molecular_function	protein-containing complex binding
A	0045428	biological_process	regulation of nitric oxide biosynthetic process
A	0065003	biological_process	protein-containing complex assembly
B	0004857	molecular_function	enzyme inhibitor activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0009890	biological_process	negative regulation of biosynthetic process
B	0016020	cellular_component	membrane
B	0016597	molecular_function	amino acid binding
B	0019899	molecular_function	enzyme binding
B	0030425	cellular_component	dendrite
B	0030742	molecular_function	GTP-dependent protein binding
B	0031965	cellular_component	nuclear membrane
B	0032991	cellular_component	protein-containing complex
B	0042470	cellular_component	melanosome
B	0042802	molecular_function	identical protein binding
B	0044549	molecular_function	GTP cyclohydrolase binding
B	0044877	molecular_function	protein-containing complex binding
B	0045428	biological_process	regulation of nitric oxide biosynthetic process
B	0065003	biological_process	protein-containing complex assembly
C	0004857	molecular_function	enzyme inhibitor activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0009890	biological_process	negative regulation of biosynthetic process
C	0016020	cellular_component	membrane
C	0016597	molecular_function	amino acid binding
C	0019899	molecular_function	enzyme binding
C	0030425	cellular_component	dendrite
C	0030742	molecular_function	GTP-dependent protein binding
C	0031965	cellular_component	nuclear membrane
C	0032991	cellular_component	protein-containing complex
C	0042470	cellular_component	melanosome
C	0042802	molecular_function	identical protein binding
C	0044549	molecular_function	GTP cyclohydrolase binding
C	0044877	molecular_function	protein-containing complex binding
C	0045428	biological_process	regulation of nitric oxide biosynthetic process
C	0065003	biological_process	protein-containing complex assembly
D	0004857	molecular_function	enzyme inhibitor activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0009890	biological_process	negative regulation of biosynthetic process
D	0016020	cellular_component	membrane
D	0016597	molecular_function	amino acid binding
D	0019899	molecular_function	enzyme binding
D	0030425	cellular_component	dendrite
D	0030742	molecular_function	GTP-dependent protein binding
D	0031965	cellular_component	nuclear membrane
D	0032991	cellular_component	protein-containing complex
D	0042470	cellular_component	melanosome
D	0042802	molecular_function	identical protein binding
D	0044549	molecular_function	GTP cyclohydrolase binding
D	0044877	molecular_function	protein-containing complex binding
D	0045428	biological_process	regulation of nitric oxide biosynthetic process
D	0065003	biological_process	protein-containing complex assembly
E	0004857	molecular_function	enzyme inhibitor activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0009890	biological_process	negative regulation of biosynthetic process
E	0016020	cellular_component	membrane
E	0016597	molecular_function	amino acid binding
E	0019899	molecular_function	enzyme binding
E	0030425	cellular_component	dendrite
E	0030742	molecular_function	GTP-dependent protein binding
E	0031965	cellular_component	nuclear membrane
E	0032991	cellular_component	protein-containing complex
E	0042470	cellular_component	melanosome
E	0042802	molecular_function	identical protein binding
E	0044549	molecular_function	GTP cyclohydrolase binding
E	0044877	molecular_function	protein-containing complex binding
E	0045428	biological_process	regulation of nitric oxide biosynthetic process
E	0065003	biological_process	protein-containing complex assembly

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE K E 1500

Chain	Residue
E	THR7
E	GLN8
E	ARG10
E	VAL13
E	GLY14

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE K C 1501

Chain	Residue
C	GLY14
C	THR7
C	GLN8
C	ARG10
C	VAL13

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE K D 1502

Chain	Residue
D	THR7
D	GLN8
D	ARG10
D	VAL13
D	GLY14

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE K B 1503

Chain	Residue
B	THR7
B	GLN8
B	ARG10
B	VAL13
B	GLY14

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site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE K A 1504

Chain	Residue
A	THR7
A	GLN8
A	ARG10
A	VAL13
A	GLY14

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