1J35

Crystal Structure of Ca(II)-bound Gla Domain of Factor IX Complexed with Binding Protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0005576	cellular_component	extracellular region
A	0035821	biological_process	modulation of process of another organism
A	0046872	molecular_function	metal ion binding
A	0090729	molecular_function	toxin activity
B	0005509	molecular_function	calcium ion binding
B	0005576	cellular_component	extracellular region
B	0035821	biological_process	modulation of process of another organism
B	0046872	molecular_function	metal ion binding
B	0090729	molecular_function	toxin activity
C	0005509	molecular_function	calcium ion binding
C	0005576	cellular_component	extracellular region

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA C 501

Chain	Residue
A	GLU98
B	HOH617
C	CGU426
C	CGU430

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 502

Chain	Residue
B	HOH643
C	CGU408
C	CGU427
C	CGU430
C	HOH655

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA C 503

Chain	Residue
C	CGU408
C	CGU417
C	CGU427
C	CGU430
C	HOH625
C	HOH636
C	HOH661

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 504

Chain	Residue
C	TYR401
C	ASN402
C	CGU407
C	CGU408
C	CGU417
C	CGU427

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 505

Chain	Residue
C	TYR401
C	CGU407
C	CGU417
C	CGU421
C	HOH692
C	HOH705

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 506

Chain	Residue
C	CGU421
C	HOH675
C	HOH708
C	HOH740
C	HOH810

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA C 507

Chain	Residue
C	CGU415
C	CGU420
C	HOH776

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 508

Chain	Residue
C	CGU436
C	CGU440
C	HOH654
C	HOH725
C	HOH840

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 511

Chain	Residue
A	SER41
A	GLU43
A	GLU47
A	GLU128
A	HOH603
A	HOH823

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 512

Chain	Residue
B	SER241
B	GLN243
B	GLU247
B	GLU320
B	HOH822
B	HOH829

---

Functional Information from PROSITE/UniProt

site_id	PS00011
Number of Residues	26
Details	GLA_1 Vitamin K-dependent carboxylation domain. EckEEkCsfeearEvfentektte.FW

Chain	Residue	Details
C	CGU417-TRP442

---

site_id	PS00615
Number of Residues	26
Details	C_TYPE_LECTIN_1 C-type lectin domain signature. CLgleketgfrk..WVNIYCgqqnp.FVC

Chain	Residue	Details
A	CYS102-CYS127
B	CYS296-CYS319

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	250
Details	Domain: {"description":"C-type lectin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00040","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10339409","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12695512","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16165155","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1J34","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1J35","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1X2T","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10339409","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12695512","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16165155","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9187649","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IXX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1J34","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1J35","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1X2T","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---