1J35

Crystal Structure of Ca(II)-bound Gla Domain of Factor IX Complexed with Binding Protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0005576	cellular_component	extracellular region
A	0035821	biological_process	modulation of process of another organism
A	0038023	molecular_function	signaling receptor activity
A	0046872	molecular_function	metal ion binding
A	0090729	molecular_function	toxin activity
B	0005509	molecular_function	calcium ion binding
B	0005576	cellular_component	extracellular region
B	0035821	biological_process	modulation of process of another organism
B	0038023	molecular_function	signaling receptor activity
B	0046872	molecular_function	metal ion binding
B	0090729	molecular_function	toxin activity
C	0005509	molecular_function	calcium ion binding
C	0005576	cellular_component	extracellular region

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA C 501

Chain	Residue
A	GLU98
B	HOH617
C	CGU426
C	CGU430

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 502

Chain	Residue
B	HOH643
C	CGU408
C	CGU427
C	CGU430
C	HOH655

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA C 503

Chain	Residue
C	CGU408
C	CGU417
C	CGU427
C	CGU430
C	HOH625
C	HOH636
C	HOH661

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 504

Chain	Residue
C	TYR401
C	ASN402
C	CGU407
C	CGU408
C	CGU417
C	CGU427

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 505

Chain	Residue
C	TYR401
C	CGU407
C	CGU417
C	CGU421
C	HOH692
C	HOH705

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 506

Chain	Residue
C	CGU421
C	HOH675
C	HOH708
C	HOH740
C	HOH810

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA C 507

Chain	Residue
C	CGU415
C	CGU420
C	HOH776

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 508

Chain	Residue
C	CGU436
C	CGU440
C	HOH654
C	HOH725
C	HOH840

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 511

Chain	Residue
A	SER41
A	GLU43
A	GLU47
A	GLU128
A	HOH603
A	HOH823

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 512

Chain	Residue
B	SER241
B	GLN243
B	GLU247
B	GLU320
B	HOH822
B	HOH829

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Functional Information from PROSITE/UniProt

site_id	PS00011
Number of Residues	26
Details	GLA_1 Vitamin K-dependent carboxylation domain. EckEEkCsfeearEvfentektte.FW

Chain	Residue	Details
C	CGU417-TRP442

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site_id	PS00615
Number of Residues	26
Details	C_TYPE_LECTIN_1 C-type lectin domain signature. CLgleketgfrk..WVNIYCgqqnp.FVC

Chain	Residue	Details
A	CYS102-CYS127
B	CYS296-CYS319

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:10339409, ECO:0000269|PubMed:12695512, ECO:0000269|PubMed:16165155, ECO:0000269|PubMed:9187649, ECO:0007744|PDB:1BJ3, ECO:0007744|PDB:1IXX, ECO:0007744|PDB:1J34, ECO:0007744|PDB:1J35, ECO:0007744|PDB:1X2T

Chain	Residue	Details
B	SER241
B	GLN243
B	GLU247
B	GLU320

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:10339409, ECO:0000269|PubMed:12695512, ECO:0000269|PubMed:16165155, ECO:0007744|PDB:1BJ3, ECO:0007744|PDB:1J34, ECO:0007744|PDB:1J35, ECO:0007744|PDB:1X2T

Chain	Residue	Details
A	SER41
A	GLU43
A	GLU47
A	GLU128

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