1IIN

thymidylyltransferase complexed with UDP-glucose

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
A	0009058	biological_process	biosynthetic process
A	0009103	biological_process	lipopolysaccharide biosynthetic process
A	0009243	biological_process	O antigen biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0019305	biological_process	dTDP-rhamnose biosynthetic process
A	0045226	biological_process	extracellular polysaccharide biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
B	0009058	biological_process	biosynthetic process
B	0009103	biological_process	lipopolysaccharide biosynthetic process
B	0009243	biological_process	O antigen biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0019305	biological_process	dTDP-rhamnose biosynthetic process
B	0045226	biological_process	extracellular polysaccharide biosynthetic process
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
C	0009058	biological_process	biosynthetic process
C	0009103	biological_process	lipopolysaccharide biosynthetic process
C	0009243	biological_process	O antigen biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0019305	biological_process	dTDP-rhamnose biosynthetic process
C	0045226	biological_process	extracellular polysaccharide biosynthetic process
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
D	0009058	biological_process	biosynthetic process
D	0009103	biological_process	lipopolysaccharide biosynthetic process
D	0009243	biological_process	O antigen biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016779	molecular_function	nucleotidyltransferase activity
D	0019305	biological_process	dTDP-rhamnose biosynthetic process
D	0045226	biological_process	extracellular polysaccharide biosynthetic process
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	25
Details	BINDING SITE FOR RESIDUE UPG A 1501

Chain	Residue
A	LEU9
A	LEU109
A	ASP111
A	ASN112
A	TYR146
A	GLY147
A	GLU162
A	LYS163
A	VAL173
A	ARG195
A	THR201
A	GLY11
A	TRP224
A	HOH1506
A	HOH1518
A	HOH1549
A	HOH1566
A	HOH1697
A	GLY12
A	ARG16
A	GLN27
A	GLN83
A	PRO86
A	ASP87
A	GLY88

---

site_id	AC2
Number of Residues	24
Details	BINDING SITE FOR RESIDUE UPG B 1502

Chain	Residue
B	LEU9
B	GLY11
B	GLY12
B	ARG16
B	GLN27
B	GLN83
B	PRO86
B	ASP87
B	GLY88
B	LEU89
B	LEU109
B	ASP111
B	ASN112
B	TYR146
B	GLY147
B	GLU162
B	LYS163
B	VAL173
B	ARG195
B	THR201
B	HOH1503
B	HOH1521
B	HOH1541
B	HOH1583

---

site_id	AC3
Number of Residues	25
Details	BINDING SITE FOR RESIDUE UPG C 1503

Chain	Residue
C	GLY11
C	GLY12
C	ARG16
C	GLN27
C	PRO86
C	LEU109
C	ASP111
C	TYR146
C	GLY147
C	GLU162
C	LYS163
C	VAL173
C	GLY175
C	TYR177
C	ARG195
C	GLU197
C	THR201
C	HOH1511
C	HOH1533
C	HOH1541
C	HOH1551
C	HOH1554
C	HOH1600
C	HOH1618
C	HOH1671

---

site_id	AC4
Number of Residues	21
Details	BINDING SITE FOR RESIDUE UPG D 1504

Chain	Residue
D	LEU9
D	GLY11
D	GLY12
D	GLN26
D	GLN27
D	GLN83
D	PRO86
D	ASP87
D	GLY88
D	ASP111
D	TYR146
D	GLY147
D	GLU162
D	LYS163
D	VAL173
D	ARG195
D	THR201
D	HOH1527
D	HOH1535
D	HOH1536
D	HOH1546

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P61887

Chain	Residue	Details
A	ASP111
A	ASP226
B	ASP111
B	ASP226
C	ASP111
C	ASP226
D	ASP111
D	ASP226

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