1IIM
thymidylyltransferase complexed with TTP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000271 | biological_process | polysaccharide biosynthetic process |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| A | 0009243 | biological_process | O antigen biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000271 | biological_process | polysaccharide biosynthetic process |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| B | 0009243 | biological_process | O antigen biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE TTP A 501 |
| Chain | Residue |
| A | LEU9 |
| A | GLN83 |
| A | PRO86 |
| A | ASP87 |
| A | GLY88 |
| A | LEU89 |
| A | GLY110 |
| A | ASP111 |
| A | HOH521 |
| A | HOH540 |
| A | HOH545 |
| A | GLY11 |
| A | HOH590 |
| A | GLY12 |
| A | SER13 |
| A | GLY14 |
| A | THR15 |
| A | ARG16 |
| A | GLN26 |
| A | GLN27 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE TTP B 502 |
| Chain | Residue |
| A | GLY219 |
| A | ARG220 |
| A | GLY221 |
| A | HOH624 |
| B | LEU46 |
| B | TYR115 |
| B | GLY116 |
| B | HIS117 |
| B | ASP118 |
| B | PRO120 |
| B | SER252 |
| B | GLU256 |
| B | ILE257 |
| B | ARG260 |
| B | HOH510 |
| B | HOH524 |
| B | HOH533 |
| B | HOH543 |
| B | HOH586 |
| B | HOH618 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE TTP B 503 |
| Chain | Residue |
| B | LEU9 |
| B | GLY11 |
| B | GLY12 |
| B | SER13 |
| B | GLY14 |
| B | THR15 |
| B | ARG16 |
| B | GLN27 |
| B | GLN83 |
| B | PRO86 |
| B | ASP87 |
| B | GLY88 |
| B | LEU89 |
| B | GLY110 |
| B | ASP111 |
| B | HOH558 |
| B | HOH570 |
| B | HOH573 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE TTP A 504 |
| Chain | Residue |
| A | LEU46 |
| A | TYR115 |
| A | GLY116 |
| A | HIS117 |
| A | ASP118 |
| A | PRO120 |
| A | SER252 |
| A | GLU256 |
| A | ILE257 |
| A | ARG260 |
| A | HOH505 |
| A | HOH584 |
| A | HOH591 |
| A | HOH605 |
| A | HOH678 |
| B | GLY219 |
| B | ARG220 |
| B | GLY221 |
| B | HOH527 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P61887","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hv9 |
| Chain | Residue | Details |
| A | ARG16 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hv9 |
| Chain | Residue | Details |
| B | ARG16 |
