1IC4
CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A)-HEN LYSOZYME COMPLEX
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| H | 0002250 | biological_process | adaptive immune response |
| H | 0002376 | biological_process | immune system process |
| H | 0003823 | molecular_function | antigen binding |
| H | 0005576 | cellular_component | extracellular region |
| H | 0016064 | biological_process | immunoglobulin mediated immune response |
| H | 0019814 | cellular_component | immunoglobulin complex |
| L | 0002250 | biological_process | adaptive immune response |
| L | 0002376 | biological_process | immune system process |
| L | 0005576 | cellular_component | extracellular region |
| L | 0005886 | cellular_component | plasma membrane |
| L | 0006955 | biological_process | immune response |
| L | 0019814 | cellular_component | immunoglobulin complex |
| Y | 0003796 | molecular_function | lysozyme activity |
| Y | 0003824 | molecular_function | catalytic activity |
| Y | 0005515 | molecular_function | protein binding |
| Y | 0005576 | cellular_component | extracellular region |
| Y | 0005615 | cellular_component | extracellular space |
| Y | 0005737 | cellular_component | cytoplasm |
| Y | 0005783 | cellular_component | endoplasmic reticulum |
| Y | 0016231 | molecular_function | beta-N-acetylglucosaminidase activity |
| Y | 0016787 | molecular_function | hydrolase activity |
| Y | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| Y | 0016998 | biological_process | cell wall macromolecule catabolic process |
| Y | 0031640 | biological_process | killing of cells of another organism |
| Y | 0042742 | biological_process | defense response to bacterium |
| Y | 0042802 | molecular_function | identical protein binding |
| Y | 0050829 | biological_process | defense response to Gram-negative bacterium |
| Y | 0050830 | biological_process | defense response to Gram-positive bacterium |
| Y | 0051672 | biological_process | obsolete catabolism by organism of cell wall peptidoglycan in other organism |
Functional Information from PROSITE/UniProt
| site_id | PS00128 |
| Number of Residues | 19 |
| Details | GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC |
| Chain | Residue | Details |
| Y | CYS76-CYS94 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 22 |
| Details | Region: {"description":"Framework-1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Region: {"description":"Complementarity-determining-1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Region: {"description":"Framework-2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Region: {"description":"Complementarity-determining-2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 31 |
| Details | Region: {"description":"Framework-3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | Region: {"description":"Complementarity-determining-3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 128 |
| Details | Domain: {"description":"C-type lysozyme","evidences":[{"source":"PROSITE-ProRule","id":"PRU00680","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Active site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Binding site: {} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 132l |
| Chain | Residue | Details |
| Y | GLU35 | |
| Y | ASP52 |
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 203 |
| Chain | Residue | Details |
