1HZF

C4ADG FRAGMENT OF HUMAN COMPLEMENT FACTOR C4A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005615	cellular_component	extracellular space

Functional Information from PROSITE/UniProt

site_id	PS00477
Number of Residues	9
Details	ALPHA_2_MACROGLOBULIN Alpha-2-macroglobulin family thiolester region signature. PrGCGEQtM

Chain	Residue	Details
A	PRO988-MSE996

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:18780401, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218

Chain	Residue	Details
A	TYR1296

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: Isoglutamyl cysteine thioester (Cys-Gln)

Chain	Residue	Details
A	PRO978
A	VAL981

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site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Responsible for effective binding to form amide bonds with immune aggregates or protein antigens

Chain	Residue	Details
A	GLN1093

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: O-linked (GalNAc...) threonine => ECO:0000269|PubMed:23234360

Chain	Residue	Details
A	GLY1212

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	a catalytic site defined by CSA, PubMed 12367531, 9041627

Chain	Residue	Details
A	CYS991
A	GLN994

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