Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000302 | biological_process | response to reactive oxygen species |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0008785 | molecular_function | alkyl hydroperoxide reductase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016668 | molecular_function | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor |
| A | 0045454 | biological_process | cell redox homeostasis |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0051287 | molecular_function | NAD binding |
| A | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 800 |
| Chain | Residue |
| A | ARG430 |
| A | ARG432 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 801 |
| Chain | Residue |
| A | LYS179 |
| A | ILE437 |
| A | HIS438 |
| A | SER439 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 900 |
| Chain | Residue |
| A | GLN496 |
| A | FAD700 |
| A | ASN257 |
| A | HIS347 |
| A | CYS348 |
| site_id | AC4 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE FAD A 700 |
| Chain | Residue |
| A | GLY219 |
| A | GLY221 |
| A | PRO222 |
| A | ALA223 |
| A | GLU243 |
| A | ARG244 |
| A | GLY247 |
| A | GLN248 |
| A | ASN257 |
| A | GLN288 |
| A | SER289 |
| A | ALA290 |
| A | ALA321 |
| A | THR322 |
| A | GLY323 |
| A | CYS345 |
| A | GLY487 |
| A | ASP488 |
| A | LYS495 |
| A | GLN496 |
| A | ILE497 |
| A | ALA500 |
| A | CL900 |
| A | HOH905 |
| A | HOH907 |
| A | HOH909 |
| A | HOH910 |
| A | HOH913 |
| A | HOH925 |
| A | HOH940 |
| A | HOH956 |
| A | HOH987 |
| A | HOH1071 |
Functional Information from PROSITE/UniProt
| site_id | PS00573 |
| Number of Residues | 21 |
| Details | PYRIDINE_REDOX_2 Pyridine nucleotide-disulphide oxidoreductases class-II active site. CphCDGpl..FkgkrVaVIGGGN |
| Chain | Residue | Details |
| A | CYS345-ASN365 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP214 | |
| A | ARG357 | |
| A | THR478 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1tde |
| Chain | Residue | Details |
| A | CYS345 | |
| A | CYS348 | |
| A | ASP349 | |
