Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004459 | molecular_function | L-lactate dehydrogenase (NAD+) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006089 | biological_process | lactate metabolic process |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0042867 | biological_process | pyruvate catabolic process |
| A | 0102443 | molecular_function | L-2-hydroxycarboxylate dehydrogenase (NAD+) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAP A 748 |
| Chain | Residue |
| A | GLY7 |
| A | THR81 |
| A | GLY83 |
| A | VAL84 |
| A | ARG86 |
| A | ILE102 |
| A | TYR106 |
| A | ILE121 |
| A | THR122 |
| A | ASN123 |
| A | LEU146 |
| A | SER9 |
| A | HIS178 |
| A | GLU219 |
| A | HOH1003 |
| A | HOH1007 |
| A | HOH1019 |
| A | HOH1046 |
| A | GLY10 |
| A | ARG11 |
| A | VAL12 |
| A | ARG34 |
| A | HIS36 |
| A | SER37 |
| A | ASN68 |
Functional Information from PROSITE/UniProt
| site_id | PS00064 |
| Number of Residues | 7 |
| Details | L_LDH L-lactate dehydrogenase active site. IGEHGDS |
| Chain | Residue | Details |
| A | ILE175-SER181 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P61889","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11292347","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P61889","evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1emd |
| Chain | Residue | Details |
| A | ASP151 | |
| A | HIS178 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1emd |
| Chain | Residue | Details |
| A | ASP151 | |
| A | ARG154 | |
| A | HIS178 | |
