1HOZ
CRYSTAL STRUCTURE OF AN INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE FROM TRYPANOSOMA VIVAX
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
A | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
A | 0046872 | molecular_function | metal ion binding |
B | 0006139 | biological_process | nucleobase-containing compound metabolic process |
B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
B | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE CA A 328 |
Chain | Residue |
A | ASP10 |
A | ASP15 |
A | THR137 |
A | ASP261 |
A | GOL1267 |
A | HOH1376 |
A | HOH1438 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE CA B 328 |
Chain | Residue |
B | ASP15 |
B | THR137 |
B | ASP261 |
B | HOH1304 |
B | HOH1427 |
B | HOH1428 |
B | ASP10 |
B | ASP14 |
site_id | AC3 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE GOL A 1267 |
Chain | Residue |
A | ASP14 |
A | THR137 |
A | MET164 |
A | ASN173 |
A | GLU184 |
A | ASN186 |
A | ASP261 |
A | CA328 |
A | HOH1376 |
A | HOH1438 |
site_id | AC4 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 1268 |
Chain | Residue |
A | MET54 |
A | PHE66 |
A | PRO67 |
A | ILE108 |
A | GLU111 |
A | ASN112 |
A | TYR115 |
site_id | AC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL B 1269 |
Chain | Residue |
A | PRO201 |
A | GLY202 |
B | LEU203 |
B | PRO303 |
B | LEU304 |
B | HOH1316 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL B 1270 |
Chain | Residue |
B | MET54 |
B | PHE66 |
B | PRO67 |
B | GLU111 |
B | ASN112 |
B | TYR115 |
site_id | AC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL A 1271 |
Chain | Residue |
A | ARG30 |
A | LEU31 |
A | PRO64 |
A | LEU65 |
A | HOH1316 |
site_id | AC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL A 1272 |
Chain | Residue |
A | SER24 |
A | ASN25 |
A | THR26 |
A | GLU27 |
A | HOH1340 |
site_id | AC9 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 1273 |
Chain | Residue |
A | LEU203 |
A | PRO303 |
A | LEU304 |
A | PHE306 |
A | HOH1331 |
A | HOH1343 |
A | HOH1418 |
site_id | BC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A 1274 |
Chain | Residue |
A | SER141 |
A | ALA144 |
A | TRP145 |
A | ASP148 |
A | SER193 |
A | HOH1299 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1r4f |
Chain | Residue | Details |
A | ASN186 | |
A | ASP10 | |
A | TRP83 | |
A | TRP260 |
site_id | CSA2 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1r4f |
Chain | Residue | Details |
B | ASN186 | |
B | ASP10 | |
B | TRP83 | |
B | TRP260 |