1HLE

CRYSTAL STRUCTURE OF CLEAVED EQUINE LEUCOCYTE ELASTASE INHIBITOR DETERMINED AT 1.95 ANGSTROMS RESOLUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004867	molecular_function	serine-type endopeptidase inhibitor activity
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0005769	cellular_component	early endosome
A	0030414	molecular_function	peptidase inhibitor activity
A	0032691	biological_process	negative regulation of interleukin-1 beta production
A	0044194	cellular_component	cytolytic granule

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 647A

Chain	Residue
A	GLY163
A	GLU166
A	GLU166
A	HOH718

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Functional Information from PROSITE/UniProt

site_id	PS00284
Number of Residues	11
Details	SERPIN Serpins signature. FNADHPFIFfI

Chain	Residue	Details
B	PHE364-ILE374

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"UniProtKB","id":"P30740","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P30740","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	28
Details	Region: {"description":"CARD-binding motif (CBM)","evidences":[{"source":"UniProtKB","id":"P30740","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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