1HJR

ATOMIC STRUCTURE OF THE RUVC RESOLVASE: A HOLLIDAY JUNCTION-SPECIFIC ENDONUCLEASE FROM E. COLI

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0000725	biological_process	recombinational repair
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004520	molecular_function	DNA endonuclease activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006281	biological_process	DNA repair
A	0006310	biological_process	DNA recombination
A	0006974	biological_process	DNA damage response
A	0008821	molecular_function	crossover junction DNA endonuclease activity
A	0009314	biological_process	response to radiation
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
A	0048476	cellular_component	Holliday junction resolvase complex
B	0000287	molecular_function	magnesium ion binding
B	0000725	biological_process	recombinational repair
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0004520	molecular_function	DNA endonuclease activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0006281	biological_process	DNA repair
B	0006310	biological_process	DNA recombination
B	0006974	biological_process	DNA damage response
B	0008821	molecular_function	crossover junction DNA endonuclease activity
B	0009314	biological_process	response to radiation
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
B	0048476	cellular_component	Holliday junction resolvase complex
C	0000287	molecular_function	magnesium ion binding
C	0000725	biological_process	recombinational repair
C	0003676	molecular_function	nucleic acid binding
C	0003677	molecular_function	DNA binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0004520	molecular_function	DNA endonuclease activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0006281	biological_process	DNA repair
C	0006310	biological_process	DNA recombination
C	0006974	biological_process	DNA damage response
C	0008821	molecular_function	crossover junction DNA endonuclease activity
C	0009314	biological_process	response to radiation
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding
C	0048476	cellular_component	Holliday junction resolvase complex
D	0000287	molecular_function	magnesium ion binding
D	0000725	biological_process	recombinational repair
D	0003676	molecular_function	nucleic acid binding
D	0003677	molecular_function	DNA binding
D	0004518	molecular_function	nuclease activity
D	0004519	molecular_function	endonuclease activity
D	0004520	molecular_function	DNA endonuclease activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0006281	biological_process	DNA repair
D	0006310	biological_process	DNA recombination
D	0006974	biological_process	DNA damage response
D	0008821	molecular_function	crossover junction DNA endonuclease activity
D	0009314	biological_process	response to radiation
D	0016787	molecular_function	hydrolase activity
D	0046872	molecular_function	metal ion binding
D	0048476	cellular_component	Holliday junction resolvase complex

Functional Information from PROSITE/UniProt

site_id	PS01321
Number of Residues	35
Details	RUVC Crossover junction endodeoxyribonuclease ruvC signature. GiGsAeKsQVqhmvrtllklpanpqa...DaADAlAIA

Chain	Residue	Details
A	GLY112-ALA146

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00034

Chain	Residue	Details
A	PRO8
D	PRO8
D	GLN67
D	ALA139
A	GLN67
A	ALA139
B	PRO8
B	GLN67
B	ALA139
C	PRO8
C	GLN67
C	ALA139

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00034, ECO:0000305|PubMed:7923356

Chain	Residue	Details
A	PRO8
B	PRO8
C	PRO8
D	PRO8

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00034

Chain	Residue	Details
A	GLN67
A	ALA139
B	GLN67
B	ALA139
C	GLN67
C	ALA139
D	GLN67
D	ALA139

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