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1HCP

DNA RECOGNITION BY THE OESTROGEN RECEPTOR: FROM SOLUTION TO THE CRYSTAL

Functional Information from GO Data
ChainGOidnamespacecontents
A0003700molecular_functionDNA-binding transcription factor activity
A0006355biological_processregulation of DNA-templated transcription
A0008270molecular_functionzinc ion binding
A0043565molecular_functionsequence-specific DNA binding
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 98
ChainResidue
ACYS7
ACYS10
ACYS24
ACYS27

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 99
ChainResidue
ACYS43
ACYS49
ACYS59
ACYS62

Functional Information from PROSITE/UniProt
site_idPS00031
Number of Residues27
DetailsNUCLEAR_REC_DBD_1 Nuclear hormones receptors DNA-binding region signature. CavCn.Dyasgy.HYgvwsCegCkaFFkR
ChainResidueDetails
ACYS7-ARG33

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues65
DetailsDNA_BIND: Nuclear receptor => ECO:0000255|PROSITE-ProRule:PRU00407
ChainResidueDetails
ACYS7-MET72

site_idSWS_FT_FI2
Number of Residues44
DetailsZN_FING: NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407
ChainResidueDetails
ACYS7-CYS27
ACYS43-CYS67

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PDB entries from 2024-10-30

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