1HC7

Prolyl-tRNA synthetase from Thermus thermophilus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004827	molecular_function	proline-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006412	biological_process	translation
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006433	biological_process	prolyl-tRNA aminoacylation
A	0016874	molecular_function	ligase activity
A	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
A	0046872	molecular_function	metal ion binding
A	0140101	molecular_function	catalytic activity, acting on a tRNA
B	0000166	molecular_function	nucleotide binding
B	0004812	molecular_function	aminoacyl-tRNA ligase activity
B	0004827	molecular_function	proline-tRNA ligase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006412	biological_process	translation
B	0006418	biological_process	tRNA aminoacylation for protein translation
B	0006433	biological_process	prolyl-tRNA aminoacylation
B	0016874	molecular_function	ligase activity
B	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
B	0046872	molecular_function	metal ion binding
B	0140101	molecular_function	catalytic activity, acting on a tRNA
C	0000166	molecular_function	nucleotide binding
C	0004812	molecular_function	aminoacyl-tRNA ligase activity
C	0004827	molecular_function	proline-tRNA ligase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006412	biological_process	translation
C	0006418	biological_process	tRNA aminoacylation for protein translation
C	0006433	biological_process	prolyl-tRNA aminoacylation
C	0016874	molecular_function	ligase activity
C	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
C	0046872	molecular_function	metal ion binding
C	0140101	molecular_function	catalytic activity, acting on a tRNA
D	0000166	molecular_function	nucleotide binding
D	0004812	molecular_function	aminoacyl-tRNA ligase activity
D	0004827	molecular_function	proline-tRNA ligase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006412	biological_process	translation
D	0006418	biological_process	tRNA aminoacylation for protein translation
D	0006433	biological_process	prolyl-tRNA aminoacylation
D	0016874	molecular_function	ligase activity
D	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
D	0046872	molecular_function	metal ion binding
D	0140101	molecular_function	catalytic activity, acting on a tRNA

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 490

Chain	Residue
A	CYS427
A	CYS432
A	CYS458
A	CYS461

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 490

Chain	Residue
B	CYS427
B	CYS432
B	CYS458
B	CYS461

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 490

Chain	Residue
C	CYS432
C	CYS458
C	CYS461
C	CYS427

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 490

Chain	Residue
D	CYS427
D	CYS432
D	CYS458
D	CYS461

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	116
Details	Region: {"description":"Interaction with tRNA"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11399074","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11399074","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10970866","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11399074","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1qf6

Chain	Residue	Details
A	ARG142

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1qf6

Chain	Residue	Details
B	ARG142

---

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1qf6

Chain	Residue	Details
C	ARG142

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1qf6

Chain	Residue	Details
D	ARG142

---