1H7H

The structure of CMP:2-keto-3-deoxy-manno-octonic acid synthetase and of its complexes with substrates and substrate analogues, CDP complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008690	molecular_function	3-deoxy-manno-octulosonate cytidylyltransferase activity
A	0009103	biological_process	lipopolysaccharide biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0033468	biological_process	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008690	molecular_function	3-deoxy-manno-octulosonate cytidylyltransferase activity
B	0009103	biological_process	lipopolysaccharide biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0033468	biological_process	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CDP A1246

Chain	Residue
A	PRO8
A	ASP98
A	HOH2040
A	ARG10
A	LYS19
A	HIS73
A	GLU74
A	SER75
A	ARG79
A	GLN96
A	GLY97

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site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CDP B1242

Chain	Residue
B	PRO8
B	ALA9
B	ARG10
B	LYS19
B	HIS73
B	GLU74
B	SER75
B	ARG79
B	GLN96
B	GLY97
B	HOH2005
B	HOH2187

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