1H6E

MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH CTLA-4 INTERNALIZATION PEPTIDE TTGVYVKMPPT

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006886	biological_process	intracellular protein transport
A	0016192	biological_process	vesicle-mediated transport
A	0030131	cellular_component	clathrin adaptor complex

Functional Information from PROSITE/UniProt

site_id	PS00991
Number of Residues	15
Details	CLAT_ADAPTOR_M_2 Clathrin adaptor complexes medium chain signature 2. IsFIPPdGeFeLmrY

Chain	Residue	Details
A	ILE263-TYR277

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P84092","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine; by TXK and JAK2","evidences":[{"source":"PubMed","id":"10842319","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9175836","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9813138","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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