1H21

A novel iron centre in the split-Soret cytochrome c from Desulfovibrio desulfuricans ATCC 27774

Replaces:  1DDC

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009061	biological_process	anaerobic respiration
A	0046872	molecular_function	metal ion binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
B	0009061	biological_process	anaerobic respiration
B	0046872	molecular_function	metal ion binding
B	0051537	molecular_function	2 iron, 2 sulfur cluster binding
C	0009061	biological_process	anaerobic respiration
C	0046872	molecular_function	metal ion binding
C	0051537	molecular_function	2 iron, 2 sulfur cluster binding
D	0009061	biological_process	anaerobic respiration
D	0046872	molecular_function	metal ion binding
D	0051537	molecular_function	2 iron, 2 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE HEC A1248

Chain	Residue
A	SER208
B	HIS246
B	PRO247
A	CYS209
A	CYS212
A	HIS213
A	TRP222
A	HIS233
A	HEC1249
B	LYS242
B	PHE243

---

site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEC A1249

Chain	Residue
A	CYS209
A	HIS213
A	GLY225
A	MET227
A	ASP228
A	CYS229
A	CYS232
A	HIS233
A	HEC1248
B	HIS148
B	ILE149
B	SER152
B	LYS153
B	TYR156
B	PRO231
B	ALA238
B	HEC1249

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE HEC B1248

Chain	Residue
A	TYR156
A	ALA237
A	ALA238
A	LYS242
A	HIS246
A	PRO247
B	CYS209
B	CYS212
B	HIS213
B	ALA220
B	HIS233
B	HEC1249

---

site_id	AC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEC B1249

Chain	Residue
A	HIS148
A	ILE149
A	SER152
A	LYS153
A	TYR156
A	ALA238
A	HEC1249
B	CYS209
B	HIS213
B	MET214
B	GLY225
B	MET227
B	ASP228
B	CYS229
B	CYS232
B	HIS233
B	HEC1248

---

site_id	AC5
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEC C1248

Chain	Residue
C	CYS209
C	HIS213
C	MET214
C	GLY225
C	MET227
C	ASP228
C	CYS229
C	CYS232
C	HIS233
D	HIS148
D	ILE149
D	SER152
D	LYS153
D	TYR156
D	PRO231
D	ALA238
D	HEC1248
D	HEC1250

---

site_id	AC6
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEC D1248

Chain	Residue
B	LYS23
B	LEU24
B	ASP25
C	CYS209
C	CYS212
C	HIS213
C	ALA220
C	HIS233
C	HEC1248
D	TYR156
D	ALA237
D	ALA238
D	LYS242
D	PHE243
D	HIS246
D	PRO247
D	HOH2052
D	HOH2053

---

site_id	AC7
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEC D1249

Chain	Residue
C	PRO247
D	SER208
D	CYS209
D	CYS212
D	HIS213
D	TRP222
D	HIS233
D	HEC1250
C	TYR156
C	ALA237
C	ALA238
C	LYS242
C	PHE243
C	HIS246

---

site_id	AC8
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEC D1250

Chain	Residue
C	HIS148
C	ILE149
C	SER152
C	LYS153
C	TYR156
C	PRO231
C	ALA238
C	HEC1248
D	CYS209
D	HIS213
D	GLY225
D	MET227
D	ASP228
D	CYS229
D	CYS232
D	HIS233
D	HEC1249

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
A	LYS76
C	VAL118
C	ALA179
C	GLN203
D	LYS76
D	VAL118
D	ALA179
D	GLN203
A	VAL118
A	ALA179
A	GLN203
B	LYS76
B	VAL118
B	ALA179
B	GLN203
C	LYS76

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: axial binding residue; in chain B => ECO:0000269|PubMed:12589573, ECO:0007744|PDB:1H21

Chain	Residue	Details
A	PHE180
B	PHE180
C	PHE180
D	PHE180

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: covalent; in chain A => ECO:0000269|PubMed:12589573, ECO:0007744|PDB:1H21

Chain	Residue	Details
A	ASN241
A	VAL244
B	ASN241
B	VAL244
C	ASN241
C	VAL244
D	ASN241
D	VAL244

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: axial binding residue; in chain A => ECO:0000269|PubMed:12589573, ECO:0007744|PDB:1H21

Chain	Residue	Details
A	ASN245
B	ASN245
C	ASN245
D	ASN245

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: Blocked amino end (Gly)

Chain	Residue	Details
A	ALA33
B	ALA33
C	ALA33
D	ALA33

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