1GZ5
Trehalose-6-phosphate synthase. OtsA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003825 | molecular_function | alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity |
| A | 0005992 | biological_process | trehalose biosynthetic process |
| A | 0006950 | biological_process | response to stress |
| A | 0006970 | biological_process | response to osmotic stress |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016758 | molecular_function | hexosyltransferase activity |
| A | 0070417 | biological_process | cellular response to cold |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003825 | molecular_function | alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity |
| B | 0005992 | biological_process | trehalose biosynthetic process |
| B | 0006950 | biological_process | response to stress |
| B | 0006970 | biological_process | response to osmotic stress |
| B | 0006974 | biological_process | DNA damage response |
| B | 0016758 | molecular_function | hexosyltransferase activity |
| B | 0070417 | biological_process | cellular response to cold |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0003825 | molecular_function | alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity |
| C | 0005992 | biological_process | trehalose biosynthetic process |
| C | 0006950 | biological_process | response to stress |
| C | 0006970 | biological_process | response to osmotic stress |
| C | 0006974 | biological_process | DNA damage response |
| C | 0016758 | molecular_function | hexosyltransferase activity |
| C | 0070417 | biological_process | cellular response to cold |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0003825 | molecular_function | alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity |
| D | 0005992 | biological_process | trehalose biosynthetic process |
| D | 0006950 | biological_process | response to stress |
| D | 0006970 | biological_process | response to osmotic stress |
| D | 0006974 | biological_process | DNA damage response |
| D | 0016758 | molecular_function | hexosyltransferase activity |
| D | 0070417 | biological_process | cellular response to cold |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12498887","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20077550","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GZ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WTX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12498887","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"14570926","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"20077550","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1GZ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WTX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12498887","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"14570926","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"20077550","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1GZ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UQT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UQU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WTX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Site: {"description":"Involved in alpha anomer selectivity","evidences":[{"source":"PubMed","id":"12498887","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1uqt |
| Chain | Residue | Details |
| A | ASP361 | |
| A | HIS154 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1uqt |
| Chain | Residue | Details |
| B | ASP361 | |
| B | HIS154 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1uqt |
| Chain | Residue | Details |
| C | ASP361 | |
| C | HIS154 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1uqt |
| Chain | Residue | Details |
| D | ASP361 | |
| D | HIS154 |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 622 |
| Chain | Residue | Details |
| A | HIS154 | electrostatic stabiliser |
| A | LEU365 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 2 |
| Details | M-CSA 622 |
| Chain | Residue | Details |
| B | HIS154 | electrostatic stabiliser |
| B | LEU365 | electrostatic stabiliser |
| site_id | MCSA3 |
| Number of Residues | 2 |
| Details | M-CSA 622 |
| Chain | Residue | Details |
| C | HIS154 | electrostatic stabiliser |
| C | LEU365 | electrostatic stabiliser |
| site_id | MCSA4 |
| Number of Residues | 2 |
| Details | M-CSA 622 |
| Chain | Residue | Details |
| D | HIS154 | electrostatic stabiliser |
| D | LEU365 | electrostatic stabiliser |
