Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005344 | molecular_function | oxygen carrier activity |
| A | 0005504 | molecular_function | fatty acid binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008941 | molecular_function | nitric oxide dioxygenase NAD(P)H activity |
| A | 0009636 | biological_process | response to toxic substance |
| A | 0015671 | biological_process | oxygen transport |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019825 | molecular_function | oxygen binding |
| A | 0020037 | molecular_function | heme binding |
| A | 0032843 | molecular_function | hydroperoxide reductase activity |
| A | 0046210 | biological_process | nitric oxide catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051409 | biological_process | response to nitrosative stress |
| A | 0071500 | biological_process | cellular response to nitrosative stress |
| A | 0071949 | molecular_function | FAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A1399 |
| Chain | Residue |
| A | LYS40 |
| A | PHE43 |
| A | GLN201 |
| A | GLU202 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A1400 |
| Chain | Residue |
| A | GLN271 |
| A | HIS294 |
| A | HIS302 |
| A | ALA303 |
| A | HOH2137 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A1401 |
| site_id | AC4 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE FAD A1397 |
| Chain | Residue |
| A | ASN44 |
| A | SER46 |
| A | GLN48 |
| A | ASN50 |
| A | TYR188 |
| A | ARG204 |
| A | GLN205 |
| A | TYR206 |
| A | SER207 |
| A | ALA220 |
| A | VAL221 |
| A | LYS222 |
| A | GLU224 |
| A | GLU225 |
| A | GLY227 |
| A | GLN228 |
| A | VAL229 |
| A | SER230 |
| A | VAL269 |
| A | THR272 |
| A | GLU388 |
| A | PHE390 |
| A | HOH2095 |
| A | HOH2103 |
| A | HOH2187 |
| A | HOH2188 |
| A | HOH2189 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM A1398 |
| Chain | Residue |
| A | LEU39 |
| A | ASN44 |
| A | GLN53 |
| A | ALA56 |
| A | LEU57 |
| A | ALA60 |
| A | ILE61 |
| A | ILE81 |
| A | LYS84 |
| A | HIS85 |
| A | PHE88 |
| A | ILE90 |
| A | GLN94 |
| A | TYR95 |
| A | VAL98 |
| A | LEU127 |
| A | PRO392 |
| A | HIS393 |
| A | HOH2190 |
| A | HOH2191 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 135 |
| Details | Domain: {"description":"Globin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 105 |
| Details | Domain: {"description":"FAD-binding FR-type"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 249 |
| Details | Region: {"description":"Reductase"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"11092893","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"proximal binding residue"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 7 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Site: {"description":"Involved in heme-bound ligand stabilization and O-O bond activation"} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Site: {"description":"Influences the redox potential of the prosthetic heme and FAD groups"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ndh |
| Chain | Residue | Details |
| A | TYR206 | |
